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Silymarin exacerbates p53-mediated tubular apoptosis in glycerol-induced acute kidney injury in rats
(Informa HealthcareLondonInglaterra, 2010)
Brazilian green propolis induced apoptosis in human lung cancer A549 cells through mitochondrial-mediated pathway
(2015)
Propolis effect on the growth and apoptosis of human lung adenocarcinoma (A549 cells) was investigated as well as its mechanisms. Cells were incubated with propolis for 72 h, and 3-(4,5- dimethylthiazol-2-yl)-2,5-dipheny ...
Sustained activation of p53 in confluent nucleotide excision repair-deficient cells resistant to ultraviolet-induced apoptosis
(ELSEVIER SCIENCE BV, 2008)
p53 activation is one of the main signals after DNA damage, controlling cell cycle arrest, DNA repair and apoptosis. We have previously shown that confluent nucleotide excision repair (NER)-deficient cells are more resistant ...
The role of apoptosis in the antigen-specific T cell hyporesponsiveness of paracoccidioidomycosis patients
(Elsevier B.V., 2002-11-01)
Paracoccidioidomycosis is a deep endemic mycosis associated with an antigen-specific immunodeficiency. To examine the role of apoptosis in this immunodeficiency, peripheral blood mononuclear cells (PBMC) of patients with ...
p53 Mutant Human Glioma Cells Are Sensitive to UV-C-Induced Apoptosis Due to Impaired Cyclobutane Pyrimidine Dimer Removal
(AMER ASSOC CANCER RESEARCH, 2009)
The p53 protein is a key regulator of cell responses to DNA damage, and it has been shown that It sensitizes glioma cells to the alkylating agent temozolomide by up-regulating the extrinsic apoptotic pathway, whereas it ...
Coxsackievirus 135 induced apoptosis of HeLa cells: Effects on p53 and SUMO
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2010)
Coxsackievirus B5 (CVB5), a human enterovirus of the family Picornaviridae, is a frequent cause of acute and chronic human diseases. The pathogenesis of enteroviral infections is not completely understood, and the fate of ...
Apoptosis induced by a snake venom metalloproteinase from bothrops alternatus venom in C2C12 muscle cells
(Springer, 2017)
In this study, the apoptosis inducing effects of baltergin as well as its influence on cell adhesion and migration on muscles cells in vitro were studied. Morphological analysis made by scanning electron and pase contrast ...
Apoptosis-related gene expression induced by Colombian propolis samples in canine osteosarcoma cell line
(2021-04-01)
Background and Aim: Osteosarcoma (OSA) is the most common bone tumor in canines and humans. This study aimed to assess the cytotoxic and apoptotic effects of Colombian propolis samples on a canine OSA cell line (OSCA-8) ...
Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells
(Elsevier Gmbh, Urban & Fischer Verlag, 2011-07-01)
Rutin is a flavonoid with antioxidant, vasodilatory, anti-inflammatory and immune-stimulating activities. To study the toxicity of rutin and its protective effect, this work investigated the cytotoxic, apoptosis-inducing, ...
Gonadotropin releasing hormone analogs induce apoptosis by extrinsic pathway involving p53 phosphorylation in primary cell cultures of human prostatic adenocarcinomas
(Wiley, 2009)
BACKGROUND. Gonadotropin-releasing-hormone (GnRH) analogs are widely used to block
hypothalamic–pituitary–gonadal axis and inhibit blood androgen levels in patients with
prostate cancer (PCa). In addition, GnRH analogs ...