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New insights on the role of lipid metabolism in the metabolic reprogramming of macrophages
(Frontiers Media, 2020)
Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...
Nitric oxide and superoxide anion balance in rats exposed to chronic and long term intermittent hypoxia
(Hindawi, 2014)
Work at high altitude in shifts exposes humans to a new form of chronic intermittent hypoxia, with still unknown health consequences. We have established a rat model resembling this situation, which develops a milder form ...
Energy Metabolism in Cardiac Remodeling and Heart Failure
(2013-05-01)
Fatty acids are the main substrates used by mitochondria to provide myocardial energy under normal conditions. During heart remodeling, however, the fuel preference switches to glucose. In the earlier stages of cardiac ...
Energy Metabolism in Cardiac Remodeling and Heart Failure
(2013-05-01)
Fatty acids are the main substrates used by mitochondria to provide myocardial energy under normal conditions. During heart remodeling, however, the fuel preference switches to glucose. In the earlier stages of cardiac ...
The role of oxidative stress on the pathophysiology of metabolic syndrome
(2017-01-01)
Metabolic syndrome (MetS) has a high prevalence around the world. Considering the components used to classify MetS, it is clear that it is closely related to obesity. These two conditions begin with an increase in abdominal ...
Heart metabolic disturbances in cardiovascular diseases.
(Instituto Mexicano del Seguro Social, 2003)
Iron and glutathione at the crossroad of redox metabolism in neurons
(Sociedad de Biología de Chile, 2006)
The uremic toxin methylguanidine increases the oxidative metabolism and accelerates the apoptosis of canine neutrophils
(2017-03-01)
We investigated the hypothesis that the increased concentration of plasma methylguanidine (MG) increases oxidative metabolism and accelerates apoptosis of neutrophils from dogs with chronic kidney disease (CKD). To achieve ...