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The prevalence of human papillomavirus in the oropharynx in healthy individuals in a Brazilian population
(Wiley-Blackwell, 2006-05-01)
Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true ...
Clinicopathological and prognostic profile of non-smoking and non-drinking head and neck cancer patients: a population-based comparative study
(2022-04-01)
Tobacco and alcohol consumption are the main risk factors for head and neck cancer (HNC). However, some individuals do not have a history of addiction and even so they develop the disease. This study evaluated clinicopathological ...
The prevalence of human papillomavirus in the oropharynx in healthy individuals in a Brazilian population
(Wiley-Blackwell, 2006-05-01)
Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true ...
Germline variants in DNA repair genes are associated with young-onset head and neck cancer
(2021-11-01)
The genetic predisposition to head and neck carcinomas (HNSCC) and how the known risk factors (papillomavirus infection, alcohol, and tobacco consumption) contribute to the early-onset disease are barely explored. Although ...
Comparison between computed tomography and clinical evaluation in tumour/node stage and follow-up of oral cavity and oropharyngeal cancer
(BRITISH INST RADIOLOGY, 2010)
Objectives: The aim was to verify the concordance of CT evaluation among four radiologists (two oral and maxillofacial and two medical radiologists) at the TN (tumour/node) stage and in the follow-up of oral cavity and ...
Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
(Dove Medical Press Ltd, 2014-01-01)
Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, ...
p16 (INK4a) has clinicopathological and prognostic impact on oropharynx and larynx squamous cell carcinoma
(Associação Brasileira de Divulgação Científica, 2012)
CDKN2A encodes proteins such as p16 (INK4a), which negatively regulate the cell-cycle. Molecular genetic studies have revealed that deletions in CDKN2A occur frequently in cancer. Although p16 (INK4a) may be involved in ...