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Maternal obesity is a risk factor for orofacial clefts: a meta-analysis
(Elsevier, 2015)
Orofacial clefts are the most prevalent birth defects that affect craniofacial structures and implicate genetic and environmental factors in their aetiology. Maternal metabolic state and nutrition have been related to these ...
Orofacial cleft management by short-term surgical missions in South America: literature review
(Churchill Livingstone, 2018)
© 2018 International Association of Oral and Maxillofacial Surgeons There is a growing demand for surgical care in South America, particularly for patients with congenital orofacial clefts (OFCs). Short-term surgical ...
Effects of folic acid fortification on orofacial clefts prevalence: a meta-analysis
(Cambridge University Press, 2017)
Objective: Orofacial clefts (OFC) are the most prevalent craniofacial birth defect. Folic acid (FA) supplementation has been demonstrated as an effective intervention to reduce risk of OFC occurrence. However, the effect ...
Maternal biomarkers of methylation status and non-syndromic orofacial cleft risk: a meta-analysis
(Elsevier, 2016)
Animal models have shown evidence of the role of maternal methyl donor status and its metabolism (one-carbon metabolism) in normal embryonic maxillofacial development. Nevertheless, studies in humans have shown conflicting ...
Association Between TGFB3 and Nonsyndromic Cleft Lip With or Without Cleft Palate in a Chilean Population
(ALLIANCE COMMUNICATIONS GROUP DIVISION ALLEN PRESS, 2010)
Objective: To assess the possible association between TGFB3 allele variants and nonsyndromic cleft lip with or without cleft palate in a Chilean population.
X-chromosome inactivation patterns in monozygotic twins and sib pairs discordant for nonsyndromic cleft lip and/or palate
(Wiley-Blackwell, 2007-12-15)
Nonsyndromic clefts of the lip and/or palate are common birth defects with a strong genetic component. Based on unequal gender ratios for clefting phenotypes, evidence for linkage to the X chromosome and the occurrence of ...
Nonsyndromic orofacial clefts in Chile: LINE-1 methylation and MTHFR variants
(Future Medicine, 2020)
Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker of global DNA methylation, and the effect of MTHFR functional variants on this variable. Patients & methods: ...
Nonsyndromic orofacial clefts in Chile: LINE-1 methylation and MTHFR variants
(2020)
Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker of global DNA methylation, and the effect of MTHFR functional variants on this variable. Patients & methods: ...
Oral clefts and vitamin supplementation
(Amer Cleft Palate-craniofacial Assoc, 2001-01-01)
Objectives: the evidence linking low levels of folic acid and orofacial clefting (OFC) is presently equivocal, There is stronger evidence for the role of folic acid supplementation in protection against the occurrence and ...
Oral clefts and vitamin supplementation
(Amer Cleft Palate-craniofacial Assoc, 2001-01-01)
Objectives: the evidence linking low levels of folic acid and orofacial clefting (OFC) is presently equivocal, There is stronger evidence for the role of folic acid supplementation in protection against the occurrence and ...