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Very fast dissolving acid carboxymethylcellulose-rifampicin matrix: development and solid-state characterization
(Elsevier Science, 2016-10)
One of the main obstacles to the successful treatment of tuberculosis is the poor and variable oral bioavailability of rifampicin (RIF), which is mainly due to its low hydrophilicity and dissolution rate. The aim of this ...
Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
(Dove Medical Press Ltd, 2014-01-01)
Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, ...
Improvement in the oral bioavailability and efficacy of new ezetimibe formulations—comparative study of a solid dispersion and different micellar systems
(MDPI, 2020)
Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the ...
Biorelevant dissolution media
(Springer, 2021)
Biorelevant dissolution media are aqueous solutions or suspensions whose composition and physicochemical characteristics closely resemble human fluids found along the different portions of the gastrointestinal tract, ...