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Performance of the chorion-allantoic membrane stained by trypan blue (CAM-TBS) of different concentrations of surfactant sodium dodecyl sulfate (SDS) for assessing the eye irritation potential

Silva, Ronald Santos; Ribeiro, Vanessa Lira; Silva, Cristiane Caldeira da; Presgrave, Octavio Augusto França; Delgado, Isabella Fernandes (2017)

Performance do ensaio da membrana córion-alantóide corada pelo azul tripan (CAM-TBS) frente a diferentes concentrações do tensoativo dodecil sulfato de sódio (SDS) para avaliação do potencial irritante ocular de produtos cosméticos e saneantes

Silva, Ronald Santos; Ribeiro, Vanessa Lira; Silva, Cristiane Caldeira da; Presgrave, Octavio Augusto França; Delgado, Isabella Fernandes (2014)

Determination of eye irritation potential of low-irritant products: comparison of in vitro results with the in vivo draize rabbit test

Nobrega, Andréa Martins da; Alves, Eloisa Nunes; Presgrave, Rosaura de Farias; Costa, Rodrigo Netto; Delgado, Isabella Fernandes (Instituto de Tecnologia do Paraná, 2014)

Ensaios da membrana cório-alantoide (HET-CAM e CAM-TBS): alternativas para a avaliação toxicológica de produtos com baixo potencial de irritação ocularChorioallantoic membrane assays (HET-CAM and CAM-TBS): alternative tests for performing toxicological evaluation of productswith low potential for ocular irritation

Oliveira, Amanda Gleyce Lima de; Silva, Ronald Santos; Alves, Eloisa Nunes; Presgrave, Rosaura de Farias; Presgrave, Octavio Augusto França; Delgado, Isabella Fernandes (Instituto Adolfo Lutz, 2014)

A Reassessment of the in vitro total protein content determination (TPC) with SIRC and 3T3 cells for the evaluation of the ocular irritation potential of shampoos: comparison with the in vivo Draize rabbit test

Costa, Rodrigo Netto; Abreu, Clarice Lima do Canto; Presgrave, Rosaura de Farias; Alves, Eloisa Nunes; Presgrave, Octavio Augusto França; Delgado, Isabella Fernandes (Instituto de Tecnologia do Paraná, 2015)

Safety assessment of cosmetic products, with emphasis on the ocular area: regulatory aspects and validation processes

Cancian, Maythe de Lima [UNIFESP]; Leonardi, Mauricio Saadi; Mosca, Mariane Martins; Guerra, Lucas Offenbecker; Hengeltraub, Simone Fanan; Leonardi, Gislaine Ricci [UNIFESP] (Univ São Paulo, Conjunto Quimicas, 2014-10-01)

Before marketing a cosmetic product, a series of biological assays, such as ocular irritation tests, must be conducted in order to prove that the product is safe. However, a few scientific articles mention the discussion ...

Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye

Freitas, João Carlos Borges Rolim de; Presgrave, Octavio Augusto França; Fingola, Fernando Faria; Menezes, Marco Antônio Carneiro; Vasconcellos, Mauricio Carvalho de; Schall, Virgínia Torres; Paumgartten, Francisco José Roma (Instituto Oswaldo Cruz, 2015)

Estudo da aplicabilidade do ensaio de citotoxicidade por quantificação de proteínas totais na avaliação do potencial irritante ocular de tensoativosStudy on applicability of the total protein cytotoxicity assay for predicting ocular irritancy of surfactants

Costa, Rodrigo Netto; Suomela, Clarice Lima Abreu; Presgrave, Rosaura de Farias; Alves, Eloisa Nunes; Guimarães, Anna Christina Rosa; Delgado, Isabella Fernandes (Centro Universitário de Brasília, 2015)

A reassessment of the in vitro RBC haemolysis assay with defibrinated sheep blood for the determination of the ocular irritation potential of cosmetic products: Comparison with the in vivo Draize rabbit test

ALVES, Eloisa Nunes; PRESGRAVE, Rosaura de Farias; PRESGRAVE, Octavio Augusto Franca; SABAGH, Fernanda Peres; FREITAS, Joao Carlos Borges Rolim de; CORRADO, Alexandre Pinto (FRAME, 2008)

We examined the correlation between results obtained from the in vivo Draize test for ocular irritation and in vitro results obtained from the sheep red blood cell (RBC) haemolytic assay, which assesses haemolysis and ...

The Hen's Egg Test on Chorioallantoic Membrane: An Alternative Assay for the Assessment of the Irritating Effect of Vaccine Adjuvants

Medical Science University of Santiago de Cuba; Universidade Estadual Paulista (Unesp); University of Oriente; University of Medical Science (2016-11-01)

Local reactions are the most frequent adverse event associated with vaccines. Adjuvants are major constituents of many vaccines and they are frequently involved in these reactions, associated with their irritating effect ...

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