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Avaliação do promotor OCT-4 de equinos em uma abordagem transgênica em células-tronco embrionárias de murinos
(Universidade Estadual Paulista (Unesp), 2014)
Avaliação do promotor OCT-4 de equinos em uma abordagem transgênica em células-tronco embrionárias de murinos
(Universidade Estadual Paulista (UNESP), 2014)
OCT4 silencing triggers its epigenetic repression and impairs the osteogenic and adipogenic differentiation of mesenchymal stromal cells
(Molecular Diversity Preservation International, 2019-07)
Mechanisms mediating mesenchymal stromal/stem cells’ (MSCs) multipotency are unclear. Although the expression of the pluripotency factor OCT4 has been detected in MSCs, whether it has a functional role in adult stem cells ...
Avaliação do promotor OCT-4 de equinos em uma abordagem transgênica em células-tronco embrionárias de murinos
(Universidade Estadual Paulista (Unesp), 2010-02-05)
O fator de transcrição Oct-4 é bem conservado entre as espécies e é conhecido por ser expresso em embriões e células-tronco embrionárias (CTE), sendo um importante marcador da pluripotência. Recentemente, foi relatado que ...
OCT4 expression mediates partial cardiomyocyte reprogramming of mesenchymal stromal cells
(Public Library of Science, 2017-12)
Mesenchymal stem/stromal cells (MSCs) are in numerous cell therapy clinical trials, including for injured myocardium. Acquisition of cardiomyocyte characteristics by MSCs may improve cardiac regeneration but the mechanisms ...
LINC00662 Promotes Aggressive Traits by Modulating OCT4 Expression through miR-335-5p in Gallbladder Cancer Cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation
(Public Library Science, 2018-12-03)
Human bone marrow-derived mesenchymal stem cells (hBMSCs) are important for tissue regeneration but their epigenetic regulation is not well understood. Here we investigate the ability of a non-nucleoside DNA methylation ...
Epiretinal membrane detection at the ophthalmologist level using deep learning of optical coherence tomography
Purpose: Previous deep learning studies on optical coherence tomography (OCT) mainly focused on
diabetic retinopathy and age-related macular degeneration. We proposed a deep learning model that
can identify epiretinal ...