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Cholesterol oxidation: Health hazard and the role of antioxidants in prevention
(Sociedad de Biología de Chile, 2003)
Inhibitory Effects of Red Wine Extracts on Endothelial-Dependent Adhesive Interactions with Monocytes Induced by Oxysterols
(Sociedad de Biología de Chile, 2004)
Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death
(Pergamon-Elsevier Science Ltd, 2017)
Mesenchymal stem cells (MSCs) are multipotent cells characterized by self-renewal and cellular differentiation capabilities. Oxysterols comprise a very heterogeneous group derived from cholesterol through enzymatic and ...
Synthetic nanoemulsion resembling a protein-free model of 7-ketocholesterol containing low density lipoprotein: In vitro and in vivo studies
(Sociedad de Biología de Chile, 2010)
Synthetic nanoemulsion resembling a protein-free model of 7-ketocholesterol containing low density lipoprotein: In vitro and in vivo studies
(SOC BIOLGIA CHILE, 2010)
7-ketocholesterol (7-KC) differs from cholesterol by a functional ketone group at C7. It is an oxygenated cholesterol derivative (oxysterol), commonly present in oxidized low-density lipoprotein (LDL). Oxysterols are ...
Fluorinated oxysterol analogues: Synthesis, molecular modelling and LXRβ activity
(Pergamon-Elsevier Science Ltd, 2017-01)
Liver X receptors (LXRs) are nuclear receptors that play central roles in the transcriptional control of lipid metabolism. The ability of LXRs to integrate metabolic and inflammation signalling makes them attractive targets ...
C(16)-C(22) oxygen-bridged analogues of ceDAF-12 and LXR ligands
(Elsevier Science Inc, 2016-08)
The DAF-12 receptor in nematodes and the Liver X Receptor (LXR) in mammals are structurally related transcription factors that play key roles in determining the life span of the organism. Both types of receptors are activated ...
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients
There is an urgent need to identify antivirals against the coronavirus SARS-CoV-2 in the current COVID-19
pandemic and to contain future similar emergencies early on. Specific side-chain cholesterol oxidation products of ...
Hormonal regulation of metabolism
(Wiley, 2016-04)
Given the current environment in most developed countries, it is a challenge to maintain a good balance between calories consumed and calories burned, although maintenance of metabolic balance is key to good health. ...
Fatty acids, cholesterol oxides and cholesterol in Brazilian processed chicken products
(Chiriotti EditoriPineroloItália, 2006)