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Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca2+- permeable TRPC6 channels
(Wiley, 2012-07)
The standardized extract of the St. John's wort plant (Hypericum perforatum) is commonly used to treat mild to moderate depression. Its active constituent is hyperforin, a phloroglucinol derivative that reduces the reuptake ...