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Interplay among ATP-Dependent Chromatin Remodelers Determines Chromatin Organisation in Yeast
(Multidisciplinary Digital Publishing Institute, 2020-07)
Cellular DNA is packaged into chromatin, which is composed of regularly-spaced nucleosomes with occasional gaps corresponding to active regulatory elements, such as promoters and enhancers, called nucleosome-depleted regions ...
Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination
(Cold Spring Harbor Laboratory Press, 2019-03)
Most yeast genes have a nucleosome-depleted region (NDR) at the promoter and an array of regularly spaced nucleosomes phased relative to the transcription start site. We have examined the interplay between RSC (a conserved ...
Accessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation
(Cold Spring Harbor Laboratory Press, 2019-08)
DNA accessibility is thought to be of major importance in regulating gene expression. We test this hypothesis using a restriction enzyme as a probe of chromatin structure and as a proxy for transcription factors. We measured ...
Multifunctional cytochrome c: learning new tricks from an old dog
(American Chemical Society, 2017-11)
Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible structure, particularly in the ferric form, such that it is able to sample a broad conformational space. Depending on the specific ...
On The Consistency Of Monte Carlo Track Structure Dna Damage Simulations
(AAPM - American Association of Physicists in Medicine, 2014)
Proton transport in water and DNA components: A Geant4 Monte Carlo simulation
(Elsevier Science BvAmsterdamHolanda, 2013)
Mejoramiento genético de una levadura Saccharomyces cerevisiae aislada en territorio colombiano para la fermentación de xilosa
(Universidad Nacional de ColombiaBogotá - Ciencias - Doctorado en BiotecnologíaInstituto de Biotecnología (IBUN)Facultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021-04-19)
Saccharomyces cerevisiae es la principal levadura utilizada en biotecnología en todo el
mundo, gracias a que su metabolismo y fisiología son conocidos permitiendo su
aprovechamiento en diversos procesos industriales. ...
Biología teórica, explicaciones y complejidad
(Universidad El Bosque, 2020)
De manera atávica, los biólogos trabajan en laboratorios, hacen trabajo de campo, se especializan en plantas o en insectos, por ejemplo, y ampliamente, hacen ciencia experimental y aplicada. En Colombia y en el mundo hay ...