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Diagnostic accuracy of nucleic acid amplification tests (NAATs) in urine for genitourinary tuberculosis: a systematic review and meta-analysis
(BioMed Central, 2017)
BACKGROUND: Genitourinary tuberculosis is the third most common form of extrapulmonary tuberculosis. Diagnosis is difficult because of unspecific clinical manifestations and low accuracy of conventional tests. Unfortunately, ...
A pangenome approach-based loop-mediated isothermal amplification assay for the specific and early detection of Bordetella pertussis
(Nature Research, 2023)
Despite widespread vaccination, Bordetella pertussis continues to cause pertussis infections worldwide, leaving infants at the highest risk of severe illness and death, while people around them are likely the main sources ...
Feasibility and Operational Performance of Tuberculosis Detection by Loop-Mediated Isothermal Amplification Platform in Decentralized Settings: Results from a Multicenter Study
(American Society for Microbiology, 2016)
Currently available nucleic acid amplification platforms for tuberculosis (TB) detection are not designed to be simple or inexpensive enough to implement in decentralized settings in countries with a high burden of disease. ...
Métodos de amplificação isotérmica e algumas aplicações.
(Universidade Federal do Rio Grande do NorteBrasilUFRNBiomedicina, 2016-11-29)
The creation of the PCR technique was a landmark for science, driving
technological growth and opening new possibilities for the diagnosis of human
diseases, especially infectious diseases. However, the advent of this ...
An Innovative Field-Applicable Molecular Test to Diagnose Cutaneous Leishmania Viannia spp Infections
(Public Library of Science, 2016)
Cutaneous and mucosal leishmaniasis is widely distributed in Central and South America. Leishmania of the Viannia subgenus are the most frequent species infecting humans. L. (V.) braziliensis, L. (V.) panamensis are also ...
Recombinase Polymerase Amplification Compared to Real-Time Polymerase Chain Reaction Test for the Detection of Fasciola hepatica in Human Stool
(American Society of Tropical Medicine and Hygiene, 2017)
Fasciola hepatica is the most widely distributed trematode infection in the world. Control efforts may be hindered by the lack of diagnostic capacity especially in remote endemic areas. Polymerase chain reaction (PCR)-based ...
Nucleic acid amplification techniques (NAATs) for early diagnosis of HIV-1 and HIV-2 infections
(2015-09-08)
This is the protocol for a review and there is no abstract. The objectives are as follows: Our primary objective is to assess the diagnostic accuracy (sensitivity and specificity) of NAATs (both quantitative and qualitative) ...