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Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators
(Elsevier, 2017-01)
Bacteria sense and adapt to environmental changes using two-component systems. These signaling pathways are formed by a histidine kinase that phosphorylates a response regulator (RR), which finally modulates the transcription ...
The NtrY/X two-component system of Brucella spp. acts as a redox sensor and regulates the expression of nitrogen respiration enzymes
(Wiley Blackwell Publishing, Inc, 2012-07)
Brucella spp. are facultative intracellular bacteria pathogenic for many mammalian species including humans, causing a disease called brucellosis. Learning how Brucella adapts to its intracellular niche is crucial for ...
Myelin-associated glycoprotein modulates apoptosis of motoneurons during early postnatal development via NgR/p75 NTR receptor-mediated activation of RhoA signaling pathways
(Nature Publishing Group, 2015-09)
Myelin-associated glycoprotein (MAG) is a minor constituent of nervous system myelin, selectively expressed on the periaxonal myelin wrap. By engaging multiple axonal receptors, including Nogo-receptors (NgRs), MAG exerts ...
The two-component systems PrrBA and NtrYX co-ordinately regulate the adaptation of Brucella abortus to an oxygen-limited environment
(Wiley Blackwell Publishing, Inc, 2013-03)
Brucella is the causative agent of the zoonotic disease brucellosis, which is endemic in many parts of the world. The success of Brucella as pathogen relies in its ability to adapt to the harsh environmental conditions ...
Snapshots of conformational changes of NtrX receiver domain shed light into its signal transduction mechanism
(Elsevier, 2015-10)
Brucella abortus is an important pathogenic bacterium that has to overcome oxygen deficiency in order to achieve a successful infection. Previously, we proved that a two-component system formed by the histidine kinase NtrY ...
Snapshots of Conformational Changes Shed Light into the NtrX Receiver Domain Signal Transduction Mechanism
(Elsevier, 2015-10)
Brucella abortus is an important pathogenic bacterium that has to overcome oxygen deficiency in order to achieve a successful infection. Previously, we proved that a two-component system formed by the histidine kinase NtrY ...
The Bradyrhizobium diazoefficiens two-component system NtrYX has a key role in symbiotic nitrogen fixation of soybean plants and cbb 3 oxidase expression in bacteroids
(Springer, 2019-07)
Aims: Bradyrhizobium diazoefficiens is a soil bacterium capable of establishing nitrogen-fixing symbiosis with soybean plants, an important crop for food production worldwide. This interaction is under the control of several ...