Buscar
Mostrando ítems 1-10 de 23
A Lys49-PLA2 myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling
(Cell Death and Disease (2012) 3, e343, 2012-07-05)
Lys49-PLA2 myotoxins, an important component of various viperid snake venoms, are a class of PLA2-homolog proteins deprived of catalytic activity. Similar to enzymatically active PLA2 (Asp49) and to other classes of ...
A Lys49-PLA2 myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling
(Cell Death and Disease (2012) 3, e343, 2012-07-05)
Lys49-PLA2 myotoxins, an important component of various viperid snake venoms, are a class of PLA2-homolog proteins deprived of catalytic activity. Similar to enzymatically active PLA2 (Asp49) and to other classes of ...
Immunochemical characterization of Micrurus nigrocinctus nigrocinctus venom with monoclonal and polyclonal antibodies
(1994)
Eleven murine monocloncal antibodies (MAbs) against Micrurus nigrocinctus nigrocinctus venom were produced and partially characterized. When M. n. nigrocinctus venom proteins were separated by SDS-PAGE under non-reducing ...
Immunochemical characterization of Micrurus nigrocinctus nigrocinctus venom with monoclonal and polyclonal antibodies
(1994)
Eleven murine monocloncal antibodies (MAbs) against Micrurus nigrocinctus nigrocinctus venom were produced and partially characterized. When M. n. nigrocinctus venom proteins were separated by SDS-PAGE under non-reducing ...
Mecanismo de acción de miotoxinas aisladas de venenos de serpientesMecanismo de acción de miotoxinas aisladas de venenos de serpientes
(Universidad de Costa Rica, 2016)
Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2
(2016-08-26)
The venom of Micrurus lemniscatus, a coral snake of wide geographical distribution in South America, was fractionated by reverse-phase HPLC and the fractions screened for phospholipase A2 (PLA2) activity. The major component ...
Immunochemical characterization and role in toxic activities of region 115-129 of myotoxin II, a Lys49 phospholipase A2 from Bothrops asper snake venom
(1998-10)
The region 115–129 of myotoxin II, a catalytically inactive
Lys49 phospholipase A2, was previously shown to
constitute a heparin-binding site and to be involved in
its cytolytic action in vitro. An immunochemical ...
Mecanismo de acción de miotoxinas aisladas de venenos de serpientes
(1984)
Biochemically and pharmacologically, myotoxins isolated from snake venoms can be placed in four main groups: myolaxic phospholipases A, low molecular weight basic toxins, cardiotoxins, and hemorrhagic myotoxins. The myotoxic ...
Broad cytolytic specificity of myotoxin II, a lysine-49 phospholipase A2 of Bothrops asper snake venom
(1994)
The cytotoxic activity of Bothrops asper myotoxin II, a lysine-49 phospholipase A2 isoform, on different cell types in culture, was investigated. Myotoxin II caused a dose-dependent cytolytic effect on all cell types tested, ...
Mecanismo de acción de miotoxinas aisladas de venenos de serpientes
(1984)
Biochemically and pharmacologically, myotoxins isolated from snake venoms can be placed in four main groups: myolaxic phospholipases A, low molecular weight basic toxins, cardiotoxins, and hemorrhagic myotoxins. The myotoxic ...