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Mucoadhesive Amphiphilic Methacrylic Copolymer-Functionalized Poly(epsilon-caprolactone) Nanocapsules for Nose-to-Brain Delivery of Olanzapine
(Amer Scientific Publishers, 2015-08-01)
Nose-to-brain drug delivery has been proposed to overcome the low absorption of drugs in central nervous system due to the absence of brain-blood barrier in the olfactory nerve pathway. However, the presence of a mucus ...
Nose-to-brain co-delivery of drugs for glioblastoma treatment using nanostructured system
(2021-06-15)
Mutations on the epidermal growth factor receptor (EGFR), induction of angiogenesis, and reprogramming cellular energetics are all biological features acquired by tumor cells during tumor development, and also known as the ...
Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease
(International Journal Of Nanomedicine, 2015)
Alzheimer's disease is a neurological disorder that results in cognitive and behavioral impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs, often fail due to their poor solubility, ...
Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease
(International Journal Of Nanomedicine, 2015)
Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease
(International Journal Of Nanomedicine, 2015)
Intranasal administration of gold nanoparticles designed to target the central nervous system: Fabrication and comparison between nanospheres and nanoprisms
(Elsevier, 2020)
The presence of the blood-brain barrier (BBB) limit gold nanoparticles (GNP) accumulation in central nervous system (CNS) after intravenous (IV) administration. The intranasal (IN) route has been suggested as a good strategy ...
Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route
(2020-01-01)
Nose-to-brain delivery is a promising approach to target drugs into the brain, avoiding the blood-brain barrier and other drawbacks related to systemic absorption, and enabling an effective and safer treatment of diseases ...