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Estudo in vitro dos efeitos da BMP-2 e do seu antagonista Noggin sobre a proliferação e migração celulares em carcinoma epidermóide de língua
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em Patologia OralOdontologia, 2014-02-27)
Oral squamous cell carcinoma (OSCC) is the most prevalent malignancy in the oral cavity and
reach a large number of individuals, has become an important public health problem. Studies
have demonstrated changes in ...
Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence
(International Society of Neuropathology, 2015-05)
Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined. In this study, we established several GSC-enriched ...
Polymorphisms of the noggin gene and mandibular micrognathia : a first approximation
El micrognatismo mandibular, deficiencia en el crecimiento de la mandíbula, no permite que los dientes entren en contacto durante la masticación, interfiriendo con la fonación y produciendo inclusive apnea del sueño. ...
Possible role of noggin gene in mandibular development
Antecedentes: El gen noggin (nog) es uno de los antagonistas de las proteínas morfogénicas
óseas (BMP) y tiene como función modular la señal de estas. Cuando su acción no es efectiva,
ocurre una actividad excesiva de las ...
Possible role of noggin gene in mandibular development
Antecedentes: El gen noggin (nog) es uno de los antagonistas de las proteínas morfogénicas
óseas (BMP) y tiene como función modular la señal de estas. Cuando su acción no es efectiva,
ocurre una actividad excesiva de las ...
The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient
(Academic Press Inc., 1998)
We have analyzed the role of mesoderm in the induction of the neural crest in Xenopus using expression of neural plate (Xsox-2) and neural crest (Xslug and ADAM). Conjugation experiments using different kinds of mesoderm ...
Transcriptional control by G-quadruplexes: In vivo roles and perspectives for specific intervention
(Taylor & Francis, 2017-01)
G-quadruplexes are non-canonical DNA secondary structures involved in several genomic and molecular processes. Here, we summarize the main G-quadruplex features and evidences proving the in vivo role on the transcriptional ...
Estandarización de la técnica Western Blot para la detección de los marcadores de neurodesarrollo BMP4, Noggin y CEP63 asociados a anomalías del sistema nervioso central causadas por ZIKV
(Universidad de La Salle. Escuela de Ciencias Básicas y Aplicadas. Biología, 2020)
Bone Morphogenetic Protein-4 Inhibits Corticotroph Tumor Cells: Involvement in the Retinoic Acid Inhibitory Action
(Endocrine Society, 2006-01)
The molecular mechanisms governing the pathogenesis of ACTH-secreting pituitary adenomas are still obscure. Furthermore, the pharmacological treatment of these tumors is limited. In this study, we report that bone morphogenetic ...