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Voltammetric behavior of nitrofurazone and its hydroxymethyl prodrug with potential anti-chagas activity
(2005-07-01)
Chagas' disease is a serious health problem for Latin America. The situation is worsened by the lack of efficient chemotherapy. The two available commercial drugs, benznidazole and nifurtimox, are more effective in the ...
Voltammetric behavior of nitrofurazone and its hydroxymethyl prodrug with potential anti-chagas activity
(2005-07-01)
Chagas' disease is a serious health problem for Latin America. The situation is worsened by the lack of efficient chemotherapy. The two available commercial drugs, benznidazole and nifurtimox, are more effective in the ...
A Prodrug Approach to Improve the Physico-Chemical Properties and Decrease the Genotoxicity of Nitro Compounds
(Bentham Science Publ Ltd, 2011-11-01)
In therapeutics research, the nitro compounds are part of an important group of drugs with multiple pharmacological activities. However, in drug design, the inclusion of a nitro group in a molecule changes the physico-chemical ...
A Prodrug Approach to Improve the Physico-Chemical Properties and Decrease the Genotoxicity of Nitro Compounds
(Bentham Science Publ Ltd, 2011-11-01)
In therapeutics research, the nitro compounds are part of an important group of drugs with multiple pharmacological activities. However, in drug design, the inclusion of a nitro group in a molecule changes the physico-chemical ...
A Prodrug Approach to Improve the Physico-Chemical Properties and Decrease the Genotoxicity of Nitro Compounds
(Bentham Science Publ Ltd, 2014)
Potential antichagasic prodrugs. Synthesis of mannich base of cipeptide primaquine and nitrofurazone.
(Amer Chemical Soc, 1996-03-24)
Potential antichagasic prodrugs. Synthesis of mannich base of cipeptide primaquine and nitrofurazone.
(Amer Chemical Soc, 1996-03-24)
Synthesis and in vitro evaluation of potential antichagasic hydroxymethyinitrofurazone (NFOH-121): A new nitrofurazone prodrug
(Elsevier B.V., 2003-11-03)
The synthesis of mutual prodrugs of nitrofurazone with primaquine, using specific and nonspecific spacer groups, has been previously attempted seeking selective antichagasic agents. The intermediate reaction product, ...
Synthesis and in vitro evaluation of potential antichagasic hydroxymethyinitrofurazone (NFOH-121): A new nitrofurazone prodrug
(Elsevier B.V., 2003-11-03)
The synthesis of mutual prodrugs of nitrofurazone with primaquine, using specific and nonspecific spacer groups, has been previously attempted seeking selective antichagasic agents. The intermediate reaction product, ...