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Oxidation and nitration of ribonuclease and lysozyme by peroxynitrite and myeloperoxidase
(ELSEVIER SCIENCE INC, 2009)
In spite of the many studies on protein modifications by reactive species, knowledge about the products resulting from the oxidation of protein-aromatic residues, including protein-derived radicals and their stable products, ...
Amphiphilic tricationic Zn(II)phthalocyanine provides effective photodynamic action to eradicate broad-spectrum microorganisms
(Royal Society of Chemistry, 2021-07)
A novel tricationic Zn(II)phthalocyanine derivative, (NCH3)3ZnPc3+, was synthesized by ring expansion reaction of boron(III) [2,9(10),16(17)-trinitrosubphthalocyaninato]chloride. First, the reaction of this subphthalocyanine ...
Mechanistic insight into the photodynamic effect mediated by porphyrin-fullerene C60 dyads in solution and in Staphylococcus aureus cells
(Royal Society of Chemistry, 2018-06)
The photodynamic action mechanism sensitized by a non-charged porphyrin-fullerene C60 dyad (TCP-C60) and its tetracationic analogue (TCP-C60 4+) was investigated in solution and in Staphylococcus aureus cells. The ability ...
Implementación y optimización del proceso sintético de i) complejos aminoácido - estaño IV y ii) péptidos conjugados con Ferroceno, como contribución al desarrollo de fármacos basados en moléculas organometálicas
(Bogotá - Ciencias - Maestría en Ciencias FarmacéuticasDepartamento de FarmaciaUniversidad Nacional de Colombia - Sede Bogotá, 2020-07)
Cancer is a global public health problem that is significantly affecting the Colombian population. Despite the advances made in the development and / or improvement of treatments, the morbidity / mortality rates are ...