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A Prodrug Approach to Improve the Physico-Chemical Properties and Decrease the Genotoxicity of Nitro Compounds
(Bentham Science Publ Ltd, 2011-11-01)
In therapeutics research, the nitro compounds are part of an important group of drugs with multiple pharmacological activities. However, in drug design, the inclusion of a nitro group in a molecule changes the physico-chemical ...
A Prodrug Approach to Improve the Physico-Chemical Properties and Decrease the Genotoxicity of Nitro Compounds
(Bentham Science Publ Ltd, 2011-11-01)
In therapeutics research, the nitro compounds are part of an important group of drugs with multiple pharmacological activities. However, in drug design, the inclusion of a nitro group in a molecule changes the physico-chemical ...
Comportamento térmico do 8-quinolinol e seus nitro-derivados
(Sociedade Brasileira de Química, 2001-10-01)
The compounds 5-nitro-8-quinolinol and 5,7-dinitro-8-quinolinol were obtained by nitration of the chelant 8-quinolinol. The compounds were characterized through EA, MNR, XRD, IR, TG, DTA and DSC. It was verified through ...
Comportamento térmico do 8-quinolinol e seus nitro-derivados
(Sociedade Brasileira de Química, 2001-10-01)
The compounds 5-nitro-8-quinolinol and 5,7-dinitro-8-quinolinol were obtained by nitration of the chelant 8-quinolinol. The compounds were characterized through EA, MNR, XRD, IR, TG, DTA and DSC. It was verified through ...
ESR, electrochemical and ORAC studies of nitro compounds with potential antiprotozoal activity
(2010)
Cyclic Voltammetry (CV) and electron spin resonance (ESR) techniques were used in the investigation of several potentially antiprotozoal nitro derivatives of dihydroquinoxaline and indazole. A self-protonation process ...
Nitro Radical Anion Formation from Nitro-8ubstituted Amphetamine Derivatives
(VCH Publishers. Inc., 1994)
The cyclic voltammetric characteristics of two nitroamphetamine derivatives (2-nitro-4,5dimethoxyamphetamine
and 2-nitro-4,5-methylenedioxyamphetamine) have been investigated in
different media. In mixed media (aqueous ...
Aromatic nitro substitution reaction between 4-nitro-N-n-butyl-1,8-naphthalimide and n-heptanethiol in water-methanol binary mixtures
(JOHN WILEY & SONS LTD, 2009)
The second-order rate constants of thiolysis by n-heptanethiol on 4-nitro-N-n-butyl-1,8-naphthalimide (4NBN) are strongly affected by the water-methanol binary mixture composition reaching its maximum at around 50% mole ...
Structures and vibrational spectra of nitro-benzo[a]pyrene and nitro-benzo[e]pyrene isomers: a density functional study
(International Knowledge Press, 2016-03)
Toxicity and reactivity of nitro polycyclics have been correlated with their molecular structure and electronic properties, in particular with the nitro substituent orientation. Experimental data are scarce for mononitro ...
Recent developments in the electrochemistry of some nitro compounds of biological significance
(BENTHAM SCIENCE PUBL, 2005-04)
The redox chemistry of different nitro compounds of biological significance is focused to understand how the reduction of the nitro group can play an active role in several aspects as: electroanalytical determinations, ...