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TOXINS AND DRUG DEVELOPMENT - HOW STRUCTURAL BIOLOGY MAY HELP YOU TO SEARCH NEW TOXIN INHIBITORS?
(Elsevier B.V., 2019-10-05)
Characterization of an OrtT-like toxin of Salmonella enterica serovar Houten
(Springer, 2019-07-01)
The Escherichia coli GhoT/GhoS system is a type V toxin-antitoxin system in which the antitoxin GhoS cleaves the GhoT mRNA, controlling its translation. GhoT is a small hydrophobic protein that damages bacterial membranes. ...
Shiga toxins and stx phages: highly diverse entities
(Society for General Microbiology, 2015-03)
Shiga toxins are the main virulence factors of a group of Escherichia coli strains [Shiga toxin-producing E. coli (STEC)] that cause severe human diseases, such as haemorrhagic colitis and haemolytic–uraemic syndrome. The ...
Neglected venomous animals and toxins: Underrated biotechnological tools in drug development
(2021-12-01)
Among the vast repertoire of animal toxins and venoms selected by nature and evolution, mankind opted to devote its scientific attention—during the last century—to a restricted group of animals, leaving a myriad of toxic ...
Brown spider (Loxosceles) venom toxins as potential biotools for the development of novel therapeutics
(2019-06-01)
Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological ...
Comparative studies of antisera against different toxinsNatural toxins II
(New York: Plenum, 1996, 1996)
Proteome analysis of snake venom toxins: pharmacological insights
(Expert Reviews, 2008-12-01)
Snake venoms are an extremely rich source of pharmacologically active proteins with a considerable clinical and medical potential. To date, this potential has not been fully explored, mainly because of our incomplete ...
Proteome analysis of snake venom toxins: pharmacological insights
(Expert Reviews, 2008-12-01)
Snake venoms are an extremely rich source of pharmacologically active proteins with a considerable clinical and medical potential. To date, this potential has not been fully explored, mainly because of our incomplete ...
Survey of moniliformin in corn cultivated in the state of Sao Paulo and in corn products commercialized in the city of Campinas, SP
(Soc Brasileira MicrobiologiaSao PauloBrasil, 2003)
Pore formation, polymerization, hemolytic and leukotoxic effects of a new Enterobacter cloacae toxin neutralized by antiserum
(Elsevier Gmbh, 2005-04)
A new toxin of Enterobacter cloacae was purified and studied by SDS-PAGE electrophoresis with the purpose of investigating its ability to generate polymers and their molecular mass. Monomer of 13.3 kDa and structures of ...