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In silico prediction of T- and B-cell epitopes in PmpD: First step towards to the design of a Chlamydia trachomatis vaccine
(Elsevier, 2018-04)
Background: Chlamydia trachomatis is the most common sexually transmitted bacterial infection globally. Currently, there are no vaccines available despite the efforts made to develop a protective one. Polymorphic membrane ...
Antibody specific B-cell epitope predictions: Leveraging information from antibody-antigen protein complexes
(Frontiers Media S.A., 2019-02)
B-cells can neutralize pathogenic molecules by targeting them with extreme specificity using receptors secreted or expressed on their surface (antibodies). This is achieved via molecular interactions between the paratope ...
Development of multi-epitope peptide-based vaccines against SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic involving so far more than 15 million infections and 630,211 deaths. Effective vaccines are urgently needed to prevent SARS-CoV-2 infections. ...
Development of multi-epitope peptide-based vaccines against SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic
involving so far more than 15 million infections and 630,211 deaths. Effective vaccines are
urgently needed to prevent SARS-CoV-2 infections. ...
Identification of linear B-cell epitopes on myotoxin-II, a Lys49 phospholipase A2 homologue from Bothrops asper snake venom
(2012)
Knowledge on toxin immunogenicity at the molecular level can provide valuable information
for the improvement of antivenoms, as well as for understanding toxin structure–
function relationships. The aims of this study ...
Identification of linear B-cell epitopes on myotoxin-II, a Lys49 phospholipase A2 homologue from Bothrops asper snake venom
(2012)
Knowledge on toxin immunogenicity at the molecular level can provide valuable information
for the improvement of antivenoms, as well as for understanding toxin structure–
function relationships. The aims of this study ...
Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies
(1992)
The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported. The monoclonal antibodies, MAb-3 and Mab-4, recognize different ...