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Functional Interactions between Newborn and Mature Neurons Leading to Integration into Established Neuronal Circuits
(Cell Press, 2017-06-19)
From development up to adulthood, the vertebrate brain is continuously supplied with newborn neurons that integrate into established mature circuits. However, how this process is coordinated during development remains ...
Frizzled-5 Receptor Is Involved in Neuronal Polarity and Morphogenesis of Hippocampal Neurons
(2013)
The Wnt signaling pathway plays important roles during different stages of neuronal development, including neuronal
polarization and dendritic and axonal outgrowth. However, little is known about the identity of the ...
DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex
(Oxford University Press, 2019-01)
Cortical development is controlled by transcriptional programs, which are orchestrated by transcription factors. Yet, stable inheritance of spatiooral activity of factors influencing cell fate and localization in different ...
Ric-8B is important for neuronal differentiation of human Neuroblastoma SH-SY5Y cells.
(2014)
Neuronal differentiation starts in early stages of embryonic development. In this process,
neurons acquire a defined identity which is characterized by the position of neuronal body,
the pattern of axonal projections and ...
Morphology, projection pattern, and neurochemical identity of Cajal's "centrifugal neurons": The cells of origin of the tectoventrogeniculate pathway in pigeon (Columba livia) and chicken (Gallus gallus)
(Wiley-Liss Inc., 2014)
The nucleus geniculatus lateralis pars ventralis (GLv) is a prominent retinal target in all amniotes. In birds, it is in receipt of a dense and topographically organized retinal projection. The GLv is also the target of ...
Single neuron coding of identity in the human hippocampal formation
(Cell Press, 2020-03-23)
Experimental findings show the ubiquitous presence of graded responses and tuning curves in the neocortex, particularly in visual areas [1–15]. Among these, inferotemporal-cortex (IT) neurons respond to complex visual ...
Islet-1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood
(National Academy of Sciences, 2015-04)
Food intake and body weight regulation depend on proper expression of the proopiomelanocortin gene (Pomc) in a group of neurons located in the mediobasal hypothalamus of all vertebrates. These neurons release POMC-encoded ...