Although the specific pathophysiological mechanisms underlying the development of spasticity are not fully understood, a large amount of evidence suggests that abnormalities in spinal pathways regulating the stretch reflex ...

Introduction: Chronic Noncommunicable Diseases (CNCDs) are the leading cause of mortality and premature disability in most countries of the American continent, including Brazil. Among CNCDs are Diabetes Mellitus (DM) and ...

Although the specific pathophysiological mechanisms underlying the development of spasticity are not fully understood, a large amount of evidence suggests that abnormalities in spinal pathways regulating the stretch reflex ...

A junção neuromuscular (JNM) é uma complexa região, de união entre o sistema nervoso periférico e as fibras musculares, onde ocorre a sinapse e permite a contração muscular. Devido a sua alta plasticidade, a morfologia ...

The DLG-MAGUK subfamily of proteins plays a role on the recycling and clustering of glutamate receptors (GLUR) at the postsynaptic density. discs-large1 (dlg) is the only DLG-MAGUK gene in Drosophila and originates two ...

Normal skeletal muscle functions are affected following trauma, chronic diseases, inherited neuromuscular disorders, aging, and cachexia, hampering the daily activities and quality of life of the affected patients. The ...