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The Netrin-4/Neogenin-1 axis promotes neuroblastoma cell survival and migration
(Impact Journals LLC, 2017)
Neogenin-1 (NEO1) is a transmembrane receptor involved in axonal guidance, angiogenesis, neuronal cell migration and cell death, during both embryonic development and adult homeostasis. It has been described as a dependence ...
Netrin-1 in glioblastoma neovascularization: the new partner in crime?
(MDPI, 2021)
Glioblastoma (GBM) is the most aggressive and common primary tumor of the central nervous system. It is characterized by having an infiltrating growth and by the presence of an excessive and aberrant vasculature. Some of ...
Downregulation of the Netrin-1 receptor UNC5B underlies increased placental angiogenesis in human gestational diabetes mellitus
(MDPI AG, 2019)
Gestational diabetes mellitus (GDM) is a common metabolic disorder, defined by high blood glucose levels during pregnancy, which affects foetal and post-natal development. However, the cellular and molecular mechanisms of ...
Intra spinal administration of Netrin-1 promotes locomotor recovery after complete spinal cord transection
(Mary Ann Liebert, 2021-08)
Complete spinal cord lesions interrupt the connection of all axonal projections with their neuronal targets below and above the lesion site. In particular, the interruption of connections with the neurons at lumbar segments ...
Downregulation of the Netrin-1 receptor UNC5b underlies increased placental angiogenesis in human gestational diabetes mellitus
(2019)
Gestational diabetes mellitus (GDM) is a common metabolic disorder, defined by high blood glucose levels during pregnancy, which affects foetal and post-natal development. However, the cellular and molecular mechanisms of ...
The Netrin-1-Neogenin-1 signaling axis controls neuroblastoma cell migration via integrin-beta 1 and focal adhesion kinase activation
(Taylor & Francis, 2021)
Neuroblastoma is a highly metastatic tumor that emerges from neural crest cell progenitors. Focal
Adhesion Kinase (FAK) is a regulator of cell migration that binds to the receptor Neogenin-1 and is
upregulated in ...
The netrin-4/ neogenin-1 axis promotes neuroblastoma cell survival and migration
(2017)
Neogenin-1 (NEO1) is a transmembrane receptor involved in axonal guidance, angiogenesis, neuronal cell migration and cell death, during both embryonic development and adult homeostasis. It has been described as a dependence ...