Buscar
Mostrando ítems 1-10 de 32
Effect of nebivolol on beat-to-beat and short-term blood pressure variability in spontaneously hypertensive rats
(Springer, 2012-08)
Cardiovascular effects and pharmacokinetics of nebivolol were assessed in spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) animals. Male SH and WKY rats were treated with vehicle or nebivolol 0.3, 3, or 10 mg ...
Nebivolol: impact on cardiac and endothelial function and clinical utility
(Dove Medical Press, 2012-03)
Endothelial dysfunction is a systemic pathological state of the endothelium characterized by a reduction in the bioavailability of vasodilators, essentially nitric oxide, leading to impaired endothelium-dependent vasodilation, ...
In Vivo and in Vitro Effects of Nebivolol on Penile Structures in Hypertensive Rats
(Oxford University Press, 2006-12)
Background: Erectile dysfunction is associated with high blood pressure and antihypertensive treatment, especially diuretics and traditional β-blockers. Nevertheless, new β-blockers such as nebivolol present some differences ...
Enantioselective pharmacokinetics and cardiovascular effects of nebivolol in L-NAME hypertensive rats
(Nature Publishing Group, 2014-03)
The cardiovascular effects and pharmacokinetics of nebivolol were assessed in N(G)-nitro-l-arginine methyl ester (L-NAME) hypertensive and normotensive control rats. Male Wistar rats were randomly divided to drink tap water ...
Nebivolol Increases Nitric Oxide Synthase via beta(3) Adrenergic Receptor in Endothelial Cells Following Exposure to Plasma from Preeclamptic Patients
(Mdpi, 2022-03-01)
Background: Low bioavailability of nitric oxide (NO) is related to the pathophysiology of preeclampsia (PE). In the present study, we investigated the effect of nebivolol (NEB), a beta(3)-receptor agonist with vasodilator ...
Perfil farmacocinético y farmacodinámico del nebivolol en un modelo experimental de síndrome metabólicoPharmacokinetic and Pharmacodynamic Profile of Nebivolol in an Animal Model of Metabolic Syndrome
(Sociedad Argentina de Cardiología, 2015-04)
Con el objetivo en este estudio de evaluar los efectos cardiovasculares y la farmacocinética del nebivolol en ratas hipertensas por sobrecarga de fructosa y en ratas control, se registraron los efectos de la administración ...