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Cytotoxic terpenoids from Nardophyllum bryoides
(Pergamon-Elsevier Science Ltd, 2010-08)
The investigation of the ethanol extract of fresh aerial parts of the Patagonian shrub Nardophyllum bryoides collected in the province of Chubut, Argentina, yielded eleven terpenoids. These include: three seco-ent-halimane ...
Effect of secochiliolide acid isolated from the Patagonian shrub Nardophyllum bryoides as active component in antifouling paints
(Elsevier, 2014-04)
Environmental concerns about the use of toxic antifoulants have led to an increased interest in the development of new alternatives. So far, most of the antifouling natural products have been obtained from marine organisms. ...
Secochiliolide ester derivatives: Preparation and evaluation of their antitrypanosomal and antimalarial efficacy
(Wiley Blackwell Publishing, Inc, 2019-02-01)
In the present study, a series of new esters of secochiliolide acid (SA), a diterpene isolated from Nardophyllum bryoides, were synthesized in good yield. All compounds were evaluated for their in vitro antiparasitic ...
Búsqueda de nuevas sustancias bioactivas a partir de productos naturales abundantesSearch for novel bioactive compounds using abundant natural products as starting materials
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2012)
Preparation and antitrypanosomal activity of secochiliolide acid derivatives
(Elsevier, 2013-07-03)
Secochiliolide acid (1) isolated from the Patagonian shrub Nardophyllum bryoides, was used as a scaffold for the preparation of a series of nine derivatives. Compound 1 and its derivatives were tested against Trypanosoma ...
Búsqueda de extractos naturales con propiedades antiparasitarias y nuevos blancos moleculares para la terapia contra la enfermedad de ChagasSearch for natural extracts with antiparasitic properties and novel molecular targets for the therapy against Chagas Disease
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2016)