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Leptin and hypothalamic gene expression in early- and late-maturing Bos indicus Nellore heifers
(Sociedade Brasileira de Genética, 2008)
We investigated wether early-maturing or late-maturing Bos indicus Nellore heifers produced more leptin mRNA in adipose tissues and altered expression of hypothalamic genes related to leptin signaling. Six prepubertal and ...
Orexin and neuropeptide Y: Tissue specific expression and immunoreactivity in the hypothalamus and preoptic area of the cichlid fish Cichlasoma dimerus
(Elsevier, 2013-12)
Neuropeptide Y (NPY) and orexin are neuropeptides involved in the regulation of feeding in vertebrates. In this study we determined the NPY and orexin mRNA tissue expression and their immunoreactivity distribution in both ...
Neuropeptide Y regulates the leptin receptors in rat hypothalamic and pituitary explant cultures
(Elsevier Science, 2013-11)
The aim of this work was to investigate whether the expression of leptin receptors (OBR) in the hypothalamic–pituitary (HP) axis is regulated by the orexigenic neuropeptide Y (NPY) during ovulation. To this end, we performed ...
Bone marrow stromal cells attenuate injury-induced changes in galanin, NPY and NPY Y1 receptor expression after a sciatic nerve constriction
(Elsevier, 2009-04)
Single ligature nerve constriction (SLNC) of the rat sciatic nerve triggers neuropathic pain-related behaviors and induces changes in neuropeptide expression in primary afferent neurons. Bone marrow stromal cells (MSCs) ...
POMC and NPY mRNA expression during development is increased in rat offspring brain from mothers fed with a high fat diet
(Elsevier B.V., 2018-02-01)
Developmental programing is influenced by perinatal nutrition and it has long-lasting impacts on adult metabolism in the offspring. In particular, maternal high fat diet has been associated with increased risk of obesity ...
Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake
(Federation of American Societies for Experimental Biology, 2020-01)
To study the pathological effects of continuous hyperprolactinemia on food intake mechanisms we used female mice that lack dopamine D2 receptors in lactotropes (lacDrd2KO). These mice had lifelong hyperprolactinemia, ...
Efeitos do tratamento com neuropeptídeo Y em um modelo de vulnerabilidade ao Transtorno de Estresse Pós-Traumático induzido pela privação materna
(Universidade Federal de São Paulo, 2023-01-18)
O Transtorno de Estresse Pós-Traumático (TEPT) é caracterizado por alterações comportamentais e neurobiológicas ocasionadas por um evento traumático. Sintomas de ansiedade e depressão e uma resposta fisiológica desregulada ...
Differential patterns of expression of neuropeptide Y throughout abstinence in outbred Swiss mice classified as susceptible or resistant to ethanol-induced locomotor sensitization
(Elsevier B.V., 2014-02-01)
Several studies have focused on the negative emotional state associated with drug abstinence. the peptide NPY plays an important role given its involvement in drug addiction, anxiety, and mood disorders. Interestingly, it ...