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Family history of cancer in Brazil: is it being used?
(SpringerDordrechtHolanda, 2008)
HMSH2 and HMSH6 gene expression profiles in colorectal adenocarcinoma in patients up to 50 years of age
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
Lynch syndrome, previously called hereditary non-polyposis colorectal cancer (HNPCC), is a major mortality threat. It is an autosomal dominant disease which is caused by a germline mutation in the DNA mismatch repair (MMR), ...
Síndrome de Lynch: Caracterización genético clínica. Caso clínico
(Sociedad Médica de Santiago, 2008)
Asociación entre características clínico-patológicas, genéticas y cáncer colorrectal hereditario no polipósico en la población peruana
(Universidad Peruana de Ciencias Aplicadas (UPC)PE, 2024)
Treatment of familial adenomatous polyposis and family screening
(SOC MEDICA SANTIAGO, 2005)
Background: To reduce the mortality associated to Familial Adenomatous Polyposis (FAP), screening of close relatives of patients with the disease is crucial. Aim To analyze the result of the surgical treatment of patients ...
Lynch syndrome: selection of families by microsatellite instability and immunohistochemistry
(SOC MEDICA SANTIAGO, 2012)
Background: Selection of patients with Lynch Syndrome (LS) for a genetic study involves the application of clinical criteria. To increase the rate of identification of mutations, the use of molecular studies as Microsatellite ...
Spectrum of MLH1 and MSH2 mutations in Chilean Families with suspected Lynch syndrome
(2010)
PURPOSE: Lynch syndrome is the most common inherited syndrome of colorectal cancer, caused principally by germline mutations in MLH1 and MSH2. We report our experience with genetic screening in the diagnosis of Lynch ...
Muir-Torre Syndrome: Case report and molecular characterization Síndrome de Muir-Torre: Relato de caso e caracterização molecular
(2014)
CONTEXT: Muir-Torre syndrome is a rare autosomal dominant genodermatosis caused by mutations in the mismatch repair genes. It is characterized by the presence of sebaceous skin tumors and internal malignancies, affecting ...
Molecular diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome)
(Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina, 2016-07-01)
Lynch syndrome is the most common cause of inherited colorectal cancer, totaling 5 to 8% of all the cases with high susceptibility to this type of cancer and extracolonic cancer. It is related to germinal mutations taking ...