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Non-visual Opsins and Novel Photo-Detectors in the Vertebrate Inner Retina Mediate Light Responses Within the Blue Spectrum Region
(Springer/Plenum Publishers, 2020-11)
In recent decades, a number of novel non-visual opsin photopigments belonging to the family of G protein- coupled receptors, likely involved in a number of non-image-forming processes, have been identified and characterized ...
Illuminating the inner retina of vertebrates: Nonvisual photopigments with novel functions
(Centro de Estudios sobre Ciencia, Desarrollo y Educacion Superior, 2020-12)
Throughout evolution, the need to detect light has generated highly specialized photoreceptor cells that in vertebrates are mainly located in the retina. The most studied photodetectors within these cells are the visual ...
Non-visual photopigments effects of constant light-emitting diode light exposure on the inner retina of Wistar rats
(Frontiers Media S.A., 2017-08)
The retina is part of the central nervous system specially adapted to capture light photons and transmit this information to the brain through photosensitive retinal cells involved in visual and non-visual activities. ...
The Visual Cycle in the Inner Retina of Chicken and the Involvement of Retinal G-Protein-Coupled Receptor (RGR)
(Springer, 2017-05-17)
The vertebrate retina contains typical photoreceptor (PR) cones and rods responsible for day/night vision, respectively, and intrinsically photosensitive retinal ganglion cells (ipRGCs) involved in the regulation of ...
Melatonin prevents non-image-forming visual system alterations induced by experimental glaucoma in rats
(Springer, 2021-03)
Glaucoma is a blindness-causing disease that involves selective damage to retinal ganglion cells (RGCs) and their axons. A subset of RGCs expressing the photopigment melanopsin regulates non-image-forming visual system ...
Effect of retinal ischemia on the non-image forming visual system
(Taylor & Francis, 2014-09)
Retinal ischemic injury is an important cause of visual impairment. The loss of retinal ganglion cells (RGCs) is a key sign of retinal ischemic damage. A subset of RGCs expressing the photopigment melanopsin (mRGCs) regulates ...
Melanopsin phototransduction is repurposed by ipRGC subtypes to shape the function of distinct visual circuits
(Elsevier (Cell Press), 2018)
Abstract: Melanopsin is expressed in distinct types of intrinsically photosensitive retinal ganglion cells (ipRGCs), which drive behaviors from circadian photoentrainment to contrast detection. A major unanswered question ...
Melanopsin and the Non-visual Photochemistry in the Inner Retina of Vertebrates
(Wiley Blackwell Publishing, Inc, 2016-01)
Melanopsin (Opn4), a member of the G-protein-coupled receptor family, is a Vitamin A-based opsin in the vertebrate retina that has been shown to be involved in the synchronization of circadian rhythms, pupillary light ...
The relevance of daylight for humans
Daylight is ubiquitous and is crucial for mammalian vision as well as for non-visual input to the brain
via the intrinsically photosensitive retinal ganglion cells (ipRGCs) that express the photopigment
melanopsin. The ...
Effect of experimental diabetic retinopathy on the non-image-forming visual system
(Taylor & Francis, 2013-05)
Diabetic retinopathy is a leading cause of blindness. Intrinsically photosensitive retinal ganglion cells (ipRGCs), which express the photopigment melanopsin, are involved in non-image-forming visual responses such as ...