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Reproducción de una versión de NMR – Mouse con dispositivos disponibles en el laboratorio
(Universidad del ValleColombiaFACULTADES DE CIENCIAS NATURALES Y EXACTASFÍSICA, 2017)
Se construyo una versión básica RMN-MOUSE abierta en configuración de herradura y se caracterizó el perfil magnético en su gap, se revisó la teoría pertinente a este caso y construyo la antena de radio frecuencia con su ...
Spatially Resolved Monitoring of Drying of Hierarchical Porous Organic Networks
(American Chemical Society, 2016-02)
Evaporation kinetics of water confined in hierarchal polymeric porous media is studied by low field nuclear magnetic resonance (NMR). Systems synthesized with various degrees of cross-linker density render networks with ...
Hormone-independent mouse mammary adenocarcinomas with different metastatic potential exhibit different metabolic signatures
(MDPI AG, 2020)
The metabolic characteristics of metastatic and non-metastatic breast carcinomas remain poorly studied. In this work, untargeted Nuclear Magnetic Resonance (NMR) metabolomics was used to compare two medroxyprogesterone ...
A novel μ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors
(2012)
BACKGROUND AND PURPOSE The μ-conopeptide family is defined by its ability to block voltage-gated sodium channels (VGSCs), a property that can be used for the development of myorelaxants and analgesics. We characterized the ...
Truncatones A–D, benzo[j]fluoranthenes from Annulohypoxylon species (Xylariaceae, Ascomycota)
(Pergamon-Elsevier Science Ltd, 2016-10)
From stromata (fruiting bodies) of three xylariaceous fungi belonging to the genus Annulohypoxylon (A. leptascum, A. cf. truncatum and an unidentified Annulohypoxylon sp.), truncatone A (1), three unprecedented derivatives ...
Seco-Taondiol, an Unusual Meroterpenoid from the Chilean Seaweed Stypopodium flabelliforme and Its Gastroprotective Effect in Mouse Model
(2015)
Ten known meroterpenoids and the new meroterpenoid 7 were isolated from the Chilean seaweed Stypopodium flabelliforme as their acetylated derivatives. Furthermore, the known metabolite taondiol has been isolated for the ...
Noninvasive quantitative imaging of selective microstructure sizes via magnetic resonance
(American Physical Society, 2021-01)
Extracting quantitative microstructure information of living tissue by noninvasive imaging is an outstanding challenge for understanding disease mechanisms and allowing early stage diagnosis of pathologies. Magnetic resonance ...
Metabolic adaptations in an endocrine-related breast cancer mouse model unveil potential markers of tumor response to hormonal therapy
(Frontiers Media, 2022-03)
Breast cancer (BC) is the most common type of cancer in women and, in most cases, it is hormone-dependent (HD), thus relying on ovarian hormone activation of intracellular receptors to stimulate tumor growth. Endocrine ...
Liver fatty acid-binding protein binds monoacylglycerol in vitro and in mouse liver cytosol.
(American Society for Biochemistry and Molecular Biology, 2013-05-08)
Liver fatty acid-binding protein (LFABP; FABP1) is expressed both in liver and intestinal mucosa. Mice null for LFABP were recently shown to have altered metabolism of not only fatty acids but also monoacylglycerol, the ...
Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy
(Molecular Diversity Preservation International, 2020-05-25)
While pancreatic cancer (PC) survival rates have recently shown modest improvement, the disease remains largely incurable. Early detection of pancreatic cancer may result in improved outcomes and therefore, methods for ...