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Evaluation of NKX3.1 and C-MYC expression in canine prostatic cancer
(2018-06-01)
NKX3.1/C-MYC cross-regulation has been reported in the normal human prostate, and loss of NKX3.1 and gain of C-MYC seem to be important events in prostate cancer development and progression. The dog can be an interesting ...
Nkx-2.3 gene in mouse epidemial maturation
(Sociedad de Biología de Chile, 2009)
NKX2.5 mutations in patients with non-syndromic congenital heart disease
(ELSEVIER IRELAND LTD, 2010)
Background: Cardiac development is a complex and multifactorial biological process. Heterozygous mutations in the transcription factor NKX2.5 are between the first evidence of a genetic cause for congenital heart defects ...
Absence of mutations in PAX8, NKX2.5, and TSH receptor genes in patients with thyroid dysgenesis
(SBEM-SOC BRASIL ENDOCRINOLOGIA & METABOLOGIARIO DE JANEIRO, RJ, 2013-08-02)
Objectives: To precisely classify the various forms of TD, and then to screen for mutations in transcription factor genes active in thyroid development. Subjects and methods: Patients underwent ultrasound, thyroid scan, ...
Avaliação epigenética dos genes NKX3.1 E CDH1 e expressão do C-MYC, NKX3.1 e E-Caderina por imuno-histoquímica em microarranjo de tecido (TMA) de lesões pré-neoplásicas e neoplásicas na próstata de cãesEpigenetic evaluation of NKX3.1 and CDH1 and immunohistochemistry expression of C-MYC, NKX3.1 and E-cadherin using tissue microarray (TMA) of pre-neoplastic and neoplastic prostate of dogs
(Universidade Estadual Paulista (Unesp), 2016)
An update on genetic variants of the NKX2-5
(Wiley-liss, div John Wiley & Sons Inc., 2020-05)
NKX2-5 is a homeodomain transcription factor that plays a crucial role in heart development. It is the first gene where a single genetic variant (GV) was found to be associated with congenital heart diseases in humans. In ...
Alterations of C-MYC, NKX3.1, and E-cadherin expression in canine prostate carcinogenesis
(2013)
The dog (canis lupus familiaris) is the only other species besides humans thatdevelop spontaneous prostatic carcinomas (PCa) at a high frequency. The canine model is pri-marily utili zed for the study of the PCa molecular ...
Avaliação epigenética dos genes NKX3.1 E CDH1 e expressão do C-MYC, NKX3.1 e E-Caderina por imuno-histoquímica em microarranjo de tecido (TMA) de lesões pré-neoplásicas e neoplásicas na próstata de cães
(Universidade Estadual Paulista (Unesp), 2016-06-23)
A próstata canina é um bom modelo para estudos comparados entre o cão e o homem, uma vez que essas duas espécies desenvolvem espontaneamente carcinoma de próstata (CP). Para melhor caracterização do CP canino, a presente ...