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Possible role of seasonality and harmful algal blooms (HAB) on the oxidative and nitrosative metabolisms in hemocytes
(Elsevier Science Inc., 2020-06)
Bivalves survive to biotoxin consumption but their metabolism could be affected. The objective of this work was to study the oxidative and nitrosative changes in the hemocytes of the mussel Mytilus edulis platensis in ...
Nitrosative stress and apoptosis in non-anemic healthy rats induced by intravenous iron sucrose similars versus iron sucrose originator
(Springer, 2015-04)
Iron can both induce and inhibit nitrosative stress. Intracellular iron levels play an important role in nitric oxide (NO•) signaling mechanisms. Depending on various factors, such as the cell's redox state and transition ...
Fe, oxidative and nitrosative metabolism in the Antarctic limpet Nacella concinna
(Elsevier Science Inc, 2016-10)
The hypothesis of this work was that oxidative and nitrosative metabolism in the digestive gland (DG) of two limpet populations (intertidal and subtidal) of the Antarctic species Nacella concinna show different behavior ...
Metipranolol promotes structure and function of retinal photoreceptors in the rd10 mouse model of human retinitis pigmentosa
(Wiley Blackwell Publishing, Inc, 2019-01)
Metipranolol is a b-adrenergic receptor antagonist that is given orally for the treatment of hypertension and also applied topically to the cornea for treating glaucoma. It also inhibits nitrosative stress which has ...
Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis
(Asian Society of Andrology, 2018-11)
Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells. Peroxynitrite-induced nitrosative stress has emerged as a major cause of impaired sperm function; however, ...
Naringin attenuates liver damage in streptozotocin-induced diabetic rats
(Elsevier France-editions Scientifiques Medicales Elsevier, 2018-09)
The aim of this study was to evaluate whether NAR has a hepatoprotective role in a model of STZ-induced diabetes and to elucidate the underlying mechanisms triggered by the flavonoid. Male Wistar rats were divided into ...
Retirada do tratamento com atorvastatina e o dano por espécies reativas no córtex cerebral de ratos
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2013-02-27)
Statins are drugs used in dislipidemias treatment. These agents are reversible inhibitors of the rate-limiting enzyme in cholesterol biosynthesis,the 3-hydroxy-3-methylglutaryl-coenzyme A reductase, and preventing de ...
Espécies reativas de oxigênio e de nitrogênio, antioxidantes e marcadores de dano oxidativo em sangue humano: principais métodos analíticos para sua determinaçãoReactive oxygen and nitrogen species, antioxidants and markers of oxidative damage in human blood: main analytical methods for their determination
(Sociedade Brasileira de Química, 2007)