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Aquaporin-2 Promoter Is Synergistically Regulated by Nitric Oxide and Nuclear Factor of Activated T Cells.
(Karger, 2011-10)
Background/aims: We have previously shown that aquaporin-2 (AQP2) is down-regulated in the renal medulla of rats made hypertensive by chronic inhibition of nitric oxide synthase (NOS). It has been shown that AQP2 expression ...
Mecanismos de activación por calcio de los factores de transcripción NF-kB y NFAT en músculo esquelético
(Universidad de Chile, 2007)
Transient Receptor Potential Canonical 3 and Nuclear Factor of Activated T Cells C3 Signaling Pathway Critically Regulates Myocardial Fibrosis
(Mary Ann Liebert, 2019-06)
Aims: Cardiac fibroblasts (CFs) are emerging as major contributors to myocardial fibrosis (MF), a final common pathway of many etiologies of heart disease. Here, we studied the functional relevance of transient receptor ...
Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling
(2013-07-01)
The cysteine proteinase inhibitor cystatin C inhibited RANKL-stimulated osteoclast formation in mouse bone marrow macrophage cultures, an effect associated with decreased mRNA expression of Acp5, Calcr, Ctsk, Mmp9, Itgb3, ...
Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling
(2013-07-01)
The cysteine proteinase inhibitor cystatin C inhibited RANKL-stimulated osteoclast formation in mouse bone marrow macrophage cultures, an effect associated with decreased mRNA expression of Acp5, Calcr, Ctsk, Mmp9, Itgb3, ...
Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of A beta-Oligomers
(2016)
Increased reactive oxygen species (ROS) generation and the ensuing oxidative stress contribute to Alzheimer's disease pathology. We reported previously that amyloid-beta peptide oligomers (A beta Os) produce aberrant Ca2+ ...
Transient Receptor Potential Canonical 3 and nuclear factor of activated T cells C3 signaling pathway critically regulates myocardial fibrosis
(Mary Ann Liebert, 2019)
Abstract:
Aims: Cardiac fibroblasts (CFs) are emerging as major contributors to myocardial fibrosis (MF), a final common pathway of many etiologies of heart disease. Here, we studied the functional relevance of transient ...
NFAT isoforms regulate muscle fiber type transition without altering can during aerobic training
(2013-04-03)
The purpose of this study was to determine whether the aerobic training-induced fiber-type transition in different muscles is associated with alterations in NFAT isoforms gene expression. We hypothesized that the aerobic ...