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Lymphoid B cells induce NF-κB activation in high endothelial cells from human tonsils
(2006)
Immune surveillance depends on still poorly understood lymphocyte-endothelium interactions required for lymphocyte transendothelial migration into secondary lymphoid organs. The nuclear factor κB (NF-κB) regulatory system ...
Norepinephrine activates NF-κB transcription factor in cultured rat pineal gland
(Pergamon PressOxford, 2014-01-17)
AIMS:
The circadian rhythm in mammalian pineal melatonin secretion is modulated by norepinephrine (NE) released at night. NE interaction with β1-adrenoceptors activates PKA that phosphorylates the transcription factor ...
Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis
(2010)
Objective: To evaluate the role of nuclear factor-κB (NF-κB) in the pathogenesis of endometriosis. Design: A literature search was conducted in PubMed to identify all relevant citations. Result(s): Our findings highlight ...
Overexpression of EGR-1 modulates the activity of NF-κB and AP-1 in prostate carcinoma PC-3 and LNCaP cell lines
(2011)
To address elements that might uniquely characterize EGR-1 mediated signaling, the expression of two transcription factors, namely, nuclear factor kappa B (NF-κB) and activator protein-1 (AP-1) were studied. PC-3 and LNCaP ...
Silibinin downregulates the NF-κB pathway and NLRP1/NLRP3 inflammasomes in monocytes from pregnant women with preeclampsia
(2019-04-19)
Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether silibinin (SB) treatment of monocytes from preeclamptic women ...
Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells
(Elsevier, 2015)
Duchenne muscular dystrophy is a fatal X-linked genetic disease, caused by mutations in the dystrophin gene, which
cause functional loss of this protein. This pathology is associated with an increased production of reactive ...
Nuclear Factor κB Activation Pathways During Mycobacterium tuberculosis Infection
(Libertas Academica, 2017)
NF-κB inhibitors impair platelet activation responses
(Wiley Blackwell Publishing, Inc, 2009-12)
Background: Although platelets are anucleated cells, they express several transcription factors that exert non-genomic functions, including the positive and negative regulation of platelet activation. NF-κB is a major ...