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Neurotrophin Signaling Impairment by Viral Infections in the Central Nervous System
(SPRINGER INTERNATIONAL PUBLISHING AG, 2022)
Neurotrophins, such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin 3 (NT-3), NT-4, and NT-5, are proteins involved in several important functions of the central nervous system. The ...
Generation and characterization of mice bearing null alleles of nradd/Nrh2
(Wiley-liss, Div John Wiley & Sons Inc, 2016-12)
The Neurotrophin receptor associated death domain gene (Nradd/Nrh2/Plaidd) is a type I transmembrane protein with a unique and short N-terminal extracellular domain and a transmembrane and intracellular domain that bears ...
The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis
(BioMed Central, 2010-11)
The ability to regulate neurogenesis in the adult dentate gyrus will require further identification and characterization of the receptors regulating this process. In vitro and in vivo studies have demonstrated that ...
Modulation of P75NTR/PRONGEF as a therapeutic approach for degenerative retinopathies
(Royal Society of Chemistry, 2018)
This chapter describes the experimental validation of neurotrophins / neurotrophin receptors as therapeutic targets for the treatment of retinal neurodegenerative disorders. Neuropathies often have inflammatory or vascular ...
Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation
(NATIONAL ACADEMY OF SCIENCES, 2011)
Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation
(NATIONAL ACADEMY OF SCIENCES, 2011)