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RGMa and RGMb expression pattern during chicken development suggest unexpected roles for these repulsive guidance molecules in notochord formation, somitogenesis, and myogenesis
(WILEY-BLACKWELLHOBOKEN, 2012)
Background: Repulsive guidance molecules (RGM) are high-affinity ligands for the Netrin receptor Neogenin, and they are crucial for nervous system development including neural tube closure; neuronal and neural crest cell ...
Neurocristopathies: New insights 150 years after the neural crest discovery
(Academic Press Inc Elsevier Science, 2018-05)
The neural crest (NC) is a transient, multipotent and migratory cell population that generates an astonishingly diverse array of cell types during vertebrate development. These cells, which originate from the ectoderm in ...
Role of BMP signaling and the homeoprotein iroquois in the specification of the cranial placodal field
(Academic Press Inc Elsevier Science, 2004-08)
Different types of placodes originate at the anterior border of the neural plate but it is still an unresolved question whether individual placodes arise as distinct ectodermal specializations in situ or whether all or a ...
RE-1 silencer of transcription/neural restrictive silencer factor modulates ectodermal patterning during Xenopus development
(SOC NEUROSCIENCE, 2006-03-08)
RE-1 silencer of transcription/neural restrictive silencer factor (REST/NRSF), a transcriptional repressor, binds to the RE-1 element present in many vertebrate genes. In vitro studies indicate that REST/NRSF plays important ...
Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification
(Elife Sciences Publ., 2019)
The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In this study, we show that Tcf7l1a is one such transcription factor that acts cell-autonomously to ...
Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-γ
(2002)
The iroquois (iro) homeobox genes participate in many developmental processes both in vertebrates and invertebrates, among them are
neural plate formation and neural patterning. In this work, we study in detail Xenopus ...
The transcription factor SoxD controls neuronal guidance in the Drosophila visual system
(Nature Publishing Group, 2018)
© 2018, The Author(s). Precise control of neurite guidance during development is essential to ensure proper formation of neuronal networks and correct function of the central nervous system (CNS). How neuronal projections ...
Efecto de la infección con virus del Zika en la estructura y citoarquitectura neuronal y astroglial en encéfalos de ratones
(Bogotá - Medicina - Maestría en NeurocienciasUniversidad Nacional de Colombia - Sede Bogotá, 2020-12-04)
Zika is a disease caused by a virus that can affect different organs but when it attacks the nervous system during embryonic development, the effects are devastating. Since this neuropathology is of recent origin, the ...