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Draft genome sequence of a New Delhi Metallo-β-Lactamase (NDM-1)-Producing providencia stuartii strain isolated in Lima, Peru
(American Society for Microbiology, 2020)
Providencia stuartii is an opportunistic pathogen of the Enterobacteriales order. Here, we report the 4,594,658-bp draft genome sequence of a New Delhi metallo-β-lactamase (NDM-1)-producing Providencia stuartii strain that ...
Draft Genome Sequence of the First New Delhi Metallo-β-Lactamase (NDM-1)-Producing Escherichia coli Strain Isolated in Peru
(American Society for Microbiology, 2018)
We present here the draft genome sequence of the first New Delhi metallo-β-lactamase (NDM-1)-producing Escherichia coli strain, belonging to sequence type 155 (ST155), isolated in Peru. Assembly of this draft genome resulted ...
Lipidated β-lactamases: from bench to bedside
(Future Medicine, 2016-12)
Carbapenemases represent one of the largest clinical threats to the action of carbapenems; the last resort drugs for the treatment of healthcare-associated infections caused by Gram-negative bacteria [1]. Metallo-β-lactamases ...
Clinical Evolution of New Delhi Metallo-β-Lactamase (NDM) optimizes resistance under Zn(II) Deprivation
(American Society for Microbiology, 2018-01)
Carbapenem-resistant Enterobacteriaceae (CRE) are rapidly spreading and taking a staggering toll on all health care systems, largely due to the dissemination of genes coding for potent carbapenemases. An important family ...
Clonagem, expressão e purificação de metalo-β-lactamase do tipo NDM para o desenvolvimento de um protótipo de teste imunocromatográfico
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Membrane anchoring stabilizes and favors secretion of New Delhi metallo-β-lactamase
(Nature Publishing Group, 2016-07)
Carbapenems, 'last-resort' β-lactam antibiotics, are inactivated by zinc-dependent metallo-β-lactamases (MBLs). The host innate immune response withholds nutrient metal ions from microbial pathogens by releasing metal-chelating ...
Triton Hodge Test: Improved Protocol for Modified Hodge Test for Enhanced Detection of NDM and Other Carbapenemase Producers
(American Society for Microbiology, 2016-03)
Accurate detection of carbapenemase-producing Gram-negative bacilli is of utmost importance for the control of nosocomial spread and the initiation of appropriate antimicrobial therapy. The modified Hodge test (MHT), a ...
Co-Occurrence of NDM-5 and RmtB in a Clinical Isolate of Escherichia coli Belonging to CC354 in Latin America
(Frontiers Media, 2021-04)
New Delhi metallo-β-lactamase (NDM)-producing isolates are usually resistant to most β-lactams and other antibiotics as a result of the coexistence of several resistance markers, and they cause a variety of infections ...
Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase
(American Chemical Society, 2016-01)
Pathogenic Gram-negative bacteria resistant to almost all β-lactam antibiotics are a major public health threat. Zn(II)-dependent or metallo-β-lactamases (MBLs) produced by these bacteria inactivate most β-lactam antibiotics, ...