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Morphine withdrawal syndrome: Involvement of the dopaminergic system in prepubertal male and female mice
(Pergamon-Elsevier Science Ltd, 2005-12)
Morphine (MOR) withdrawal signs are more marked in males than in females. Considering that the influence of the dopaminergic system on these differences is unclear, we analyzed dopamine (DA) and dihydroxyphenylacetic-acid ...
Baclofen prevents the elevated plus maze behavior and BDNF expression during naloxone precipitated morphine withdrawal in male and female mice
(Wiley-liss, Div John Wiley & Sons Inc, 2016-05)
In previous studies we have shown that baclofen, a selective GABAB receptor agonist, prevents the somatic expression and reestablishes the dopamine and μ-opioid receptors levels, modified during naloxone-precipitated ...
Attenuation by baclofen of nicotine rewarding properties and nicotine withdrawal manifestations
(Springer, 2014-08)
Rationale:Nicotine is a major active ingredient in tobacco and plays a major role in tobacco addiction. In rodents, repeated nicotine administration produces behavioral responses related to its addictive properties, such ...
Baclofen did not modify sexually dimorphic c-Fos expression during morphine withdrawal syndrome
(Wiley, 2013-03)
In previous studies, we have reported sex-related differences during morphine withdrawal. We have also shown that the GABAB agonist baclofen (BAC) was able to prevent the morphine withdrawal syndrome in male as well as in ...
Extrato bruto de Vitex megapotamica apresenta efeito antinociceptivo e tipo-antidepressivo em ratos
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2016-08-12)
Vitex megapotamica (Spreng) Moldenke is a native tree of South America, popularly known as Tarumã, has been used in folk medicine to treat inflammatory diseases. Although the effects of V megapotamica in animal models of ...
Modulación de la respuesta emocional y la memoria espacial en la adultez por exposición temprana a nicotina
(Departamento de PsicologíaUniversidad Nacional de Colombia - Sede Bogotá, 2019-12-12)
The relationship between stress and nicotine has focused on how stressful events can be a risk factor for the establishment of an addiction. However, little has been explored about the inverse relationship, that is, the ...