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P120-Catenin Regulates Early Trafficking Stages of the N-Cadherin Precursor Complex
(Public Library of Science, 2016-06)
It is well established that binding of p120 catenin to the cytoplasmic domain of surface cadherin prevents cadherin endocytosis and degradation, contributing to cell-cell adhesion. In the present work we show that p120 ...
E-cadherin and beta-catenin Loss of Expression Related to Bone Metastasis in Prostate Cancer
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
Objectives: E-cadherin and beta-catenin are adhesion molecules responsible for the maintenance of normal epithelial cell phenotype. A disturbance in epithelial cell adhesion, which leads to a more invasive and metastatic ...
Immune expression of E-cadherin and alpha, beta and gamma-Catenin adhesion molecules and prognosis for upper urinary tract urothelial carcinomas
(BRAZILIAN SOC UROLRIO DE JANEIRO, 2012)
Introduction: Cell adhesion molecules (CAM) are required for maintaining a normal epithelial phenotype, and abnormalities in CAM expression have been related to cancer progression, including bladder urothelial carcinomas. ...
Role of adhesion molecules and proliferation hyperplasic, pre neoplastic and neoplastic lesions in canine prostate
(2013-05-01)
E-cadherin and beta-catenin are component of adherens junctions in epithelial cells. Loss of these proteins have been associated with progression of prostatic diseases. We performed immunohistochemistry for E-cadherin, ...
E-cadherin in canine mast cell tumors: Decreased expression and altered subcellular localization in Grade 3 tumors
(ELSEVIER SCI LTDOXFORD, 2012)
Mast cell tumors (MCTs) are the most frequent round cell tumors in dogs and comprise approximately 21% of all canine cutaneous tumors. MCTs are highly invasive and metastatic corresponding to the histological grade. ...
E-cadherin: a determinant molecule associated with ovarian cancer progression, dissemination and aggressiveness
(Public Library of Science, 2017-09)
PLoS One. 2017 Sep 21;12(9):e0184439. doi: 10.1371/journal.pone.0184439. eCollection 2017.E-cadherin: A determinant molecule associated with ovarian cancer progression, dissemination and aggressiveness.Rosso M1, Majem B2, ...
Secretory leukocyte protease inhibitor (slpi) expression downregulates E-cadherin, induces β-catenin re-localization and triggers apoptosis-related events in breast cancer cells
(Wiley, 2014-09)
BACKGROUND INFORMATION: Epithelial cadherin (E-cadherin) is involved in cell–cell adhesion through its extracellular domain, whereas the intracellular domain interacts with adaptor proteins, i.e. β-catenin, links E-cadherin ...