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Synthesis and in vitro Antifungal Evaluation of Novel N-Substituted 4-Aryl-2-methylimidazoles
(Wiley-VCH, 2018-05)
An efficient and regioselective synthesis of novel 4-aryl-2-methyl-N-phenacylimidazoles 5 by a microwave-assisted pseudo-tricomponent reaction between acetamidine hydrochloride (3) and α-bromoacetophenones 2 has been ...
Intermolecular interaction energies and molecular conformations in N -substituted 4-aryl-2-methylimidazoles with promising in vitro antifungal activity
(International Union of Crystallography, 2019-11)
A convenient one-pot synthesis of 4-aryl-2-methyl-N-phenacylimidazoles (4) through a microwave-assisted pseudo-tricomponent reaction of -bromoacetophenones (1) with acetamidine hydrochloride (2) is reported. Ketones (4) ...