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Association of myelin peptide with vitamin D prevents autoimmune encephalomyelitis development
(2016-03-11)
Multiple sclerosis is a chronic, inflammatory and demyelinating disease of the central nervous system (CNS). As there is no cure for this disease, new therapeutic strategies and prophylactic measures are necessary. We ...
Association of myelin oligodendrocyte glycoprotein with vitamin D inhibited experimental autoimmune encephalomyelitis development
(Federation Amer Soc Exp Biol, 2014-04-01)
Myelin-associated glycoprotein activation triggers glutamate uptake by oligodendrocytes in vitro and contributes to ameliorate glutamate-mediated toxicity in vivo
(Elsevier Science, 2022-04)
Background: Myelin-associated glycoprotein (MAG) is a key molecule involved in the nurturing effect of myelin on ensheathed axons. MAG also inhibits axon outgrowth after injury. In preclinical stroke models, administration ...
Myelin-associated glycoprotein modulates apoptosis of motoneurons during early postnatal development via NgR/p75 NTR receptor-mediated activation of RhoA signaling pathways
(Nature Publishing Group, 2015-09)
Myelin-associated glycoprotein (MAG) is a minor constituent of nervous system myelin, selectively expressed on the periaxonal myelin wrap. By engaging multiple axonal receptors, including Nogo-receptors (NgRs), MAG exerts ...
Tolerogenic Vaccination with MOG/VitD Overcomes Aggravating Effect of C. albicans in Experimental Encephalomyelitis
(2016-10-01)
Aims: Multiple sclerosis (MS) is an immune-mediated demyelinating disorder of the central nervous system (CNS). We described that Candida albicans (Ca) aggravates experimental autoimmune encephalomyelitis (EAE) that is a ...
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) in Chile: lessons learned from challenging cases
(2023)
Background: Anti-Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Associated Disease (MOGAD) is an emerging disorder recognized as a clinical entity distinct from Multiple Sclerosis and Aquaporin-4-positive Neuromyelitis ...
Association of myelin oligodendrocyte glycoprotein with vitamin D inhibited experimental autoimmune encephalomyelitis development
(Federation Amer Soc Exp Biol, 2015)
Gangliosides in Axon Stability and Regeneration
(Elsevier, 2018)
Gangliosides are a family of sialic acid-containing glycosphingolipids highly expressed in the nervous system of vertebrates. Over the last 25years, research has unmasked several of their neurobiological functions but the ...
Tocopherol Derivative TFA-12 Promotes Myelin Repair in Experimental Models of Multiple Sclerosis
(Society for Neuroscience, 2013-07-10)
Multiple sclerosis (MS) is an inflammatory disease of the CNS that is associated with demyelination and axonal loss, resulting in severe neurological handicap. Current MS therapies mostly target neuroinflammation but have ...
Synaptic Rearrangement Following Axonal Injury: Old And New Players
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2015)