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Insights on the Structure of Amyloid Fibrils from Site-Directed Mutagenesis
(Bentham Science Publ LtdSharjahEmirados Árabes Unidos, 2009)
LaNe RAGE: a new tool for genomic DNA flanking sequence determination
(Pontificia Universidad Católica de Valparaíso, 2005)
Insights in the kinetic mechanism of the eukaryotic Baeyer-Villiger monooxygenase BVMOAf1 from Aspergillus fumigatus Af293
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2014-12)
This work reports a detailed kinetic study of the recently discovered BVMOAf1 from Aspergillus fumigatus Af293. By performing steady state and pre-steady state kinetic analyses, it was demonstrated that the rate of catalysis ...
Mutations of triad determinants changes the substrate alignment at the catalytic center of human ALOX5.
(American Chemical Society, 2019-10)
For the specificity of ALOX15 orthologs of different mammals the geometry of the amino acids Phe353, Ile418, Met419 and Ile593 (?triad determinants?) is important and mutagenesis of these residues altered the reaction ...
Mechanisms of lindane-induced hepatotoxicity: Alterations of respiratory activity and sinusoidal glutathione efflux in the isolated perfused rat liver
(Informa Healthcare, 1991)
1. Lindane (25-60 mg/kg) at 24 h after dosage induced a dose-dependent increase in oxygen consumption by perfused rat livers, an effect not observed at early times (2-6 h) after administration. About 60% of the increase ...
The interaction of bothropstoxin-I (Lys49-PLA(2)) with liposome membranes
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Bothropstoxin-I (BthTx-I) is a Lys49-PLA(2) from the venom of the snake Bothrops jararacussu, which permeabilizes biological and artificial membranes by a mechanism independent of lipid hydrolysis. This mechanism has been ...
Anti-clastogenic effect of beta-glucan extracted from barley towards chemically induced DNA damage in rodent cells
(Hodder Arnold, Hodder Headline Plc, 2006-06-01)
beta-Glucan (BG) was tested in vitro to determine its potential clastogenic and/or anti-clastogenic activity, and attempts were made to elucidate its possible mechanism of action by using combinations with an inhibitor of ...
Anti-clastogenic effect of beta-glucan extracted from barley towards chemically induced DNA damage in rodent cells
(Hodder Arnold, Hodder Headline Plc, 2006-06-01)
beta-Glucan (BG) was tested in vitro to determine its potential clastogenic and/or anti-clastogenic activity, and attempts were made to elucidate its possible mechanism of action by using combinations with an inhibitor of ...