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Cellular and molecular mechanisms of apoptosis in skeletal muscle atrophy
(2007-12-28)
Apoptosis is necessary for maintaining the integrity of proliferative tissues, such as epithelial cells of the gastrointestinal and integumentary systems. The role of apoptosis in post-mitotic tissues, such as skeletal ...
Cellular and molecular mechanisms of apoptosis in skeletal muscle atrophy
(2007-12-28)
Apoptosis is necessary for maintaining the integrity of proliferative tissues, such as epithelial cells of the gastrointestinal and integumentary systems. The role of apoptosis in post-mitotic tissues, such as skeletal ...
High-intensity resistance training attenuates dexamethasone-induced muscle atrophy
(Wiley-Blackwell, 2015-09-10)
We investigated the effects of high-intensity resistance training (RT) on dexamethasone (DEX) induced muscle atrophy in flexor hallucis longus (FHL), tibialis anterior (TA), and soleus (SOL) muscles. Rats underwent either ...
Heart failure increases atrogin-1 and MuRF1 gene expression in skeletal muscle with fiber type-specific atrophy
(Springer, 2010-02-01)
Heart failure (HF) is characterized by a reduced tolerance to exercise due to early fatigue and dyspnea; this may be due in part to skeletal muscle myopathy with a shift from slow to fast fibers and loss of muscle mass. ...
Low-intensity resistance training attenuates dexamethasone-induced atrophy in the flexor hallucis longus muscle
(Elsevier B.V., 2014-09-01)
This study investigated the potential protective effect of low-intensity resistance training (RT) against dexamethasone (DEX) treatment induced muscle atrophy. Rats underwent either an 8 week period of ladder climbing RT ...
Myosin heavy chain expression and atrophy in rat skeletal muscle during transition from cardiac hypertrophy to heart failure
(Blackwell Publishing, 2003-08-01)
The purpose of this investigation was to determine whether changes in myosin heavy chain (MHC) expression and atrophy in rat skeletal muscle are observed during transition from cardiac hypertrophy to chronic heart failure ...
Myosin heavy chain expression and atrophy in rat skeletal muscle during transition from cardiac hypertrophy to heart failure
(Blackwell Publishing, 2003-08-01)
The purpose of this investigation was to determine whether changes in myosin heavy chain (MHC) expression and atrophy in rat skeletal muscle are observed during transition from cardiac hypertrophy to chronic heart failure ...
Time-course changes of catabolic proteins following muscle atrophy induced by dexamethasone
(2016-03-01)
This study was designed to describe the time-course changes of catabolic proteins following muscle atrophy induced by 10 days of dexamethasone (DEX). Rats underwent DEX treatment for 1, 3, 5, 7 and 10 days. Body weight ...
Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor
(Wiley, 2020)
Skeletal muscle atrophy is characterized by the degradation of myofibrillar proteins, such as myosin heavy chain or troponin. An increase in the expression of two muscle-specific E3 ligases, atrogin-1 and MuRF-1, and ...