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Regulatory T cells in dogs with multicentric lymphoma: peripheral blood quantification at diagnosis and after initial stage chemotherapy
(Arquivo Brasileiro Medicina Veterinaria Zootecnia, 2016-01-01)
Lymphoma is the most common hematopoietic malignancy in dogs and one of the most frequent among all neoplastic diseases in this species. It can occur in several anatomical locations with distinct histological and ...
Histopathological and immunophenotypical characterization of canine multicentric lymphoma in Brazil: a study of 203 cases
(Arquivo Brasileiro Medicina Veterinaria Zootecnia, 2020-05-01)
The immunophenotype is regarded as an independent prognostic factor in high-grade lymphomas, seeing that lymphomas of T-cell origin are associated with shorter survival time. Although a number of studies have evaluated the ...
Oxidative stress in dogs with multicentric lymphoma: Effect of chemotherapy on oxidative and antioxidant biomarkers
(2015-11-01)
Introduction: Lymphoma is one of the most common types of cancer in dogs, characterized by the proliferation of lymphoid cells. The treatment of this type of cancer is usually based on drugs with high toxicity, which can ...
Quantification of Treg cells in peripheral blood and lymph nodes of dogs with multicentric lymphoma
(2017-11-01)
Lymphoma is a malignant tumor characterized by cell proliferation of lymphoid origin and corresponds to 90% of all hematopoietic neoplasms of dogs. Regulatory T cells (Tregs) have been the target of many investigations in ...
Histopathological and immunophenotypical assessment of canine primary splenic lymphoma according to the World Health Organization
(2018-11-01)
Although there are several studies addressing multicentric lymphoma in dogs, data regarding splenic lymphoma remains scarce. The diagnosis of splenic lymphoma using the World Health Organization (WHO) classification system ...
Combination Chemotherapy with Firocoxib Induces Reduction of Regulatory T Cells in Dogs with Multicentric B Cell Lymphoma
(Univ Agriculture, Fac Veterinary Science, 2019-01-01)
The aim of this study was to quantify T cells (CD4+, CD8+ and Treg), in dogs with multicentric lymphoma treated with a conventional CHOP protocol or with one in which firocoxib was used instead of prednisone. Twenty-one ...
Serum concentration and immunostaining of vascular endothelial growth factor in dogs with multicentric lymphoma
(2015-01-01)
Vascular endothelium growth factor (VEGF) is one of the most specific regulators of tumor angiogenesis and lymphangiogenesis. Moreover, VEGF plays a role in tumorigenesis through activation of an autocrine signaling pathway ...
Multicentric lymphoma with metastasis in the central nervous system in a dog
(Universidade Federal de Minas Gerais (UFMG), Escola de Veterinária, 2005-06-01)
Linfoma multicêntrico foi diagnosticado em um cão com dois anos de idade que apresentava insuficiência respiratória, aumento de volume abdominal (ascite) e linfoadenopatia generalizada. O exame imunoistoquímico revelou ...
Multicentric lymphoma with metastasis in the central nervous system in a dog
(Universidade Federal de Minas Gerais (UFMG), Escola de Veterinária, 2005-06-01)
Linfoma multicêntrico foi diagnosticado em um cão com dois anos de idade que apresentava insuficiência respiratória, aumento de volume abdominal (ascite) e linfoadenopatia generalizada. O exame imunoistoquímico revelou ...