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Laboratory Mouse & COVID-19 Research
(Open Access Journal of Biomedical Science, 2020)
From chromosomal abnormalities to the identification of target genes in mouse models of breast cancer
(Elsevier Inc, 2014-06-25)
Cytogenetic studies of breast cancer cells have identified numerous chromosomal imbalances, including gains in human chromosome regions 1q, 4p, 8q, and 20q and losses in regions 1p, 3p, 6q, 11q, 16q, 17p, and 22q. Mouse ...
Human immature dental pulp stem cells` contribution to developing mouse embryos: production of human/mouse preterm chimaeras
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
In this study, we aimed at determining whether human immature dental pulp stem cells (hIDPSC) would be able to contribute to different cell types in mouse blastocysts without damaging them. Also, we analysed whether these ...
Effect of isotretinoin on tooth germ and palate development in mouse embryos.
(2001-07-11)
Vitamin A and its derivatives, retinoic acid, tretinoin and isotretinoin, are currently used in dermatological treatments. The administration of high doses of this vitamin provokes congenital malformations in mice: cleft ...
Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8a1 and human ch13q34
(American Association for Cancer Research, 2007-05-04)
Serial analysis of gene expression from aggressive mammary tumors derived from transplantable p53 null mouse mammary outgrowth lines revealed significant up-regulation of Tfdp1 (transcription factor Dp1), Lamp1 (lysosomal ...
C57BL/6 α-1,3-Galactosyltransferase knockout mouse as an animal model for experimental Chagas disease
(American Chemical Society, 2020)
The leading animal model of experimental Chagas disease, the mouse, plays a significant role in studies for vaccine development, diagnosis, and human therapies. Humans, along with Old World primates, alone among mammals, ...
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
(2004)
Stem cells are crucial for normal development and homeostasis, and their misbehavior may be related to the origin of cancer. Progress in these areas has been difficult because the mechanisms regulating stem cell lineages ...