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Interleukin-10 Produced by Myeloid-Derived Suppressor Cells Provides Protection to Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 258 by Enhancing Its Clearance in the Airways
(2019)
Carbapenem-resistant Klebsiella pneumoniae sequence type 258 (CRKP-ST258) can cause chronic infections in lungs and airways, with repeated episodes of bacteremia. In this report we addressed whether the recruitment of ...
Myeloid-derived suppressor cells impair the quality of dendritic cell vaccines
(2012)
Myeloid-derived suppressor cells (MDSC) are important regulators of the immune system and key players in tumor-induced suppression of T-cell responses. CD14+HLA-DR-/low MDSC have been detected in a great number of malignancies, ...
Expansion of a subset of CD14(high)CD16(neg)CCR2(low/neg) monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection
(FEDERATION AMER SOC EXP BIOLBETHESDA, 2012)
Monocytes have been categorized in three main subpopulations based on CD14 and CD16 surface expression. Classical monocytes express the CD14(++)CD16(-) CCR2(+) phenotype and migrate to inflammatory sites by quickly responding ...
CD11b+GR1+Myeloid Cells Secrete NGF and Promote Trigeminal Ganglion Neurite Growth: Implications for Corneal Nerve Regeneration
(Assoc Research Vision Ophthalmology Inc, 2013-09-01)
PURPOSE. We characterized fluorescent bone marrow cells (YFP+ BMCs) in the thy1-YFP mouse and determine if they promote trigeminal ganglion (TG) cell neurite growth.METHODS. Excimer laser annular keratectomy was performed ...
Estudo da modulação das células mielóides supressoras no adenocarcinoma metastático após terapia antiangiogênica
(Universidade Federal de São Paulo (UNIFESP), 2016-08-31)
Renal cell carcinoma (RCC), the third leading cause of death in genitourinary cancers. RCCs are highly vascularized and resistant to radiotherapy and chemotherapy. Antiangiogenic drugs are promising and widely used in ...
Immunoregulatory effects of Lurbinectedin in chronic lymphocytic leukemia
(Springer, 2020-02-13)
Despite significant therapeutic improvements chronic lymphocytic leukemia (CLL) remains an incurable disease and there is a persistent pursuit of new treatment alternatives. Lurbinectedin, a selective inhibitor of active ...