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Obesity as a possible risk factor for progression from monoclonal gammopathy of undetermined significance progression into multiple myeloma: could myeloma be prevented with metformin treatment?

Cunha Júnior, Ademar Dantas da; Zanette, Dalila Lucíola; Pericole, Fernando Vieira; Saad, Sara Teresinha Olalla; Carvalheira, José Barreto Campello (Hindawi, 2021)

Free light chains in serum in the diagnosis of Monoclonal GammopathiesCadenas ligeras libres en suero en el diagnóstico de Gammapatías Monoclonales

Mesa Sierra, Manuela; Jaramillo Arbeláez, Patricia; Diaz, Laura M; Gálvez, Kenny (Universidad de Córdoba, 2019)

Paraproteinemic Neuropathies: A Review For Neurologists

De León,Andrés M.; Jeanneret,Valerie (Sociedad Médica Ecuatoriana de Neurología, 2022)

Extramedullary Plasmacytoma Diagnosed In An Hiv-positive Patient By An Unusual Clinical Presentation

de Camargo Moraes; Paulo; Thomaz; Luiz Alexandre; Martins Montalli; Victor Angelo; Cintra Junqueira; Jose Luiz; Beder Ribeiro; Camila Maria; Oliveira; Luciana Butini (Hindawi Publishing CorpNew York, 2016)

Altered mRNA expression of telomere-associated genes in monoclonal gammopathy of undetermined significance and multiple myeloma

Panero, Julieta; Arbelbide, Jorge; Fantl, Dorotea Beatriz; Garcia Rivello, Hernan Jorge; Kohan, Dana; Slavutsky, Irma Rosa (Feinstein Inst Med Res, 2010-11)

In this study, we explored changes in the expression of the telomere maintenance genes, TRF1, TRF2 and TANK1 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM). Results ...

DNA methylation analysis of tumor suppressor genes in monoclonal gammopathy of undetermined significance

Stanganelli, Carmen Graciela; Arbelbide, Jorge; Fantl, Dorotea Beatriz; Corrado, Claudia; Slavutsky, Irma Rosa (Springer, 2010-02)

Aberrant DNA methylation is considered an important epigenetic mechanism for gene inactivation. Monoclonal gammopathy of undetermined significance (MGUS) is believed to be a precursor of multiple myeloma (MM). We have ...

MAGE-C1/CT7 and MAGE-C2/CT10 are frequently expressed in multiple myeloma and can be explored in combined immunotherapy for this malignancy

Carvalho, Fabricio de [UNIFESP]; Alves, Veruska L. F. [UNIFESP]; Braga, Walter M. T. [UNIFESP]; Xavier, Celso V. [UNIFESP]; Colleoni, Gisele W. B. [UNIFESP] (Springer, 2013-01-01)

The exact function of MAGE-C1/CT7 and MAGE-C2/CT10 is not yet understood in multiple myeloma (MM). However, the homologs MAGE-C1/CT7 and MAGE-C2/CT10 genes encode highly immunogeneic cancer/testis antigens (CTAs) and can ...

Frequency and prognostic relevance of cancer testis antigen 45 expression in multiple myeloma

ANDRADE, Valeria C. C.; VETTORE, Andre L.; SILVA, Maria Regina Regis; FELIX, Roberta S.; ALMEIDA, Manuella S. S.; CARVALHO, Fabricio de; ZAGO, Marco Antonio; CABALLERO, Otavia L.; SIMPSON, Andrew J.; COLLEONI, Gisele W. B. (ELSEVIER SCIENCE INC, 2009)

Objective. This study aims to analyze the expression of cancer testis antigen 45 (CT45) in normal tissues and in plasma cell disorders and to identify possible associations with clinical data and prognosis in multiple ...

Quantitative analysis of CKS1B mRNA expression and copy number gain in patients with plasma cell disorders

Stella, Flavia; Pedrazzini, Estela Marta; Baialardo, Edgardo; Fantl, Dorotea; Schutz, Natalia; Slavutsky, Irma Rosa (Academic Press Inc Elsevier Science, 2014-09)

In this study, we have examined CKS1B gene expression and copy number in a total of 114- patients at diagnosis: 83 with multiple myeloma (MM) and 31 with monoclonal gammopathy of undetermined significance (MGUS). Results ...

Differential expression of non-shelterin genes associated with high telomerase levels and telomere shortening in plasma cell disorders

Panero, Julieta; Stella, Flavia; Schutz, Natalia; Fantl, Dorotea Beatriz; Slavutsky, Irma Rosa (Public Library of Science, 2015-09-14)

Telomerase, shelterin proteins and various interacting factors, named non-shelterin proteins, are involved in the regulation of telomere length (TL). Altered expression of any of these telomere-associated genes can lead ...