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Amphetamine derivatives as monoamine oxidase inhibitors
(Frontiers Media S.A., 2020)
Amphetamine derivatives as Monoamine Oxidase Inhibitors
(Frontiers Media, 2020)
Amphetamine and its derivatives exhibit a wide range of pharmacological activities, including psychostimulant, hallucinogenic, entactogenic, anorectic, or antidepressant effects. The mechanisms of action underlying these ...
In vitro inhibition of acetylcholinesterase and monoamine oxidase by Syzygium cumini leaves extract and preliminary assessment in animal models
(2022-05-01)
Syzygium cumini (Myrtaceae) is a tropical tree used in traditional medicines to treat several diseases. All parts of S. cumini are used for medicinal purposes and present antioxidant potential. In this study, we evaluated ...
Monoamine Oxidase Inhibition In the Light of New Structural Data
(Bentham Science Publishers Ltd., 2004-11-25)
The recent description of the crystal structures of rat MAO-A and human MAO-B provides an
unprecedented framework to elucidate the mechanisms underlying the selective interactions between these
proteins and their ligands. ...
Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: Insights from molecular modeling studies
(Elsevier Ltd., 2007-05-22)
Abstract—Four enantiomerically pure (S)-4-alkylthioamphetamine derivatives were evaluated as monoamine oxidase (MAO) inhibitors
using the human and rat isoforms of the enzyme. Molecular dockings were performed in order ...
Monoamine Oxidase Inhibitory Properties of Optical Isomers and N-substituted Derivatives of 4-methylthioamphetamine
(Taylor & Francis Ltd, 2003-03-10)
(6)-4-Methylthioamphetamine (MTA) was resolved into
its enantiomers, and a series of N-alkyl derivatives of the
parent compound, as well as its a-ethyl analogue, were
prepared. The monoamine oxidase (MAO) inhibitory
properties ...
MAO inhibition by arylisopropylamines: the effect of oxygen substituents at the b-position
(Elsevier Ltd., 2004-05-26)
Abstract—Twenty-nine arylisopropylamines, substituted at the b-position of their side chain by an oxo, hydroxy, or methoxy group,
were evaluated in vitro as MAO-A and MAO-B inhibitors. The oxo derivatives (‘cathinones’) ...
Monoamine Oxidase Inhibitory Properties of Some Methoxylated and Alkylthio Amphetamine Derivatives STRUCTURE-ACTIVITY RELA TIONSHIPS
(Elsevier Science Inc., 1997)
The monoamine oxidase (MAO) inhibitory propenies of a series of amphetamine derivatives
with difTerent substituents at or around rhe para position of the aromaric ring were evaluateJ. i¡, in viero stuJies
in which a crude ...
Monoamine oxidase inhibitory properties of some methoxylated and alkylthio amphetamine derivatives. Structure-activity relationships
(1997)
The monoamine oxidase (MAO) inhibitory properties of a series of amphetamine derivatives with different substituents at or around the para position of the aromatic ring were evaluated. In in vitro studies in which a crude ...
MONOAMINE-OXIDASE INHIBITION PREVENTS ISCHEMIA-REPERFUSION DAMAGE IN RAT KIDNEYS
(ELSEVIER SCIENCE INC, 1995)