To speed up the discovery of bioactive natural products (NP), chemists have sought advanced approaches in analytical and computational chemistry in attempt to organize and extract information from large data sets. In this ...

Though introduced recently, complex networks research has grown steadily because of its potential to represent, characterize and model a wide range of intricate natural systems and phenomena. Because of the intrinsic ...

Saprobic fungus are being used as an alternative strategy to reduce the use of pesticides harmful to the environment. These microorganisms produce substances capable of inhibiting pathogens that affect agriculture. The ...

Dynamic multilevel systems can be assembled from molecular building blocks through two or more reversible reactions that form covalent bonds. Molecular networks of dynamic multilevel systems can exhibit different connectivities ...

Rhizoma Polygonati (huangjing in Chinese, 黄精) is an herb-homology-food used as a component of alternative medicine treating COVID-19 in the current pandemic emergency in China but the mechanisms remain elusive. Here using ...

Background: Hemangioma is a common benign tumor in the childhood; however our knowledge about the molecular mechanisms of hemangioma development and progression are still limited. Currently, microRNAs (miRNAs) have been ...

In this study an Artificial Neural Network was developed to predict the penetration of drugs through a polydimethylsiloxane membrane by molecular descriptors. A total of 245 drugs and their absorption experimentally ...