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Effect of the microtubule-associated protein tau on dynamics of single-headed motor proteins KIF1A
(American Physical Society, 2014-02)
Intracellular transport based on molecular motors and its regulation are crucial to the functioning of cells. Filamentary tracks of the cells are abundantly decorated with nonmotile microtubule-associated proteins, such ...
Effect of the microtubule-associated protein tau on dynamics of single-headed motor proteins KIF1A
(2014-02)
Intracellular transport based on molecular motors and its regulation are crucial to the functioning of cells. Filamentary tracks of the cells are abundantly decorated with nonmotile microtubule-associated proteins, such ...
Transition to superdiffusive behavior in intracellular actin-based transport mediated by molecular motors
(American Physical Society, 2009-12)
Intracellular transport of large cargoes, such as organelles, vesicles, or large proteins, is a complex dynamical process that involves the interplay of adenosine triphosphate-consuming molecular motors, cytoskeleton ...
Nucleotide-dependent dynamics of the Dengue NS3 helicase
(Elsevier Science, 2020-08)
Dengue represents a substantial public health burden, particularly in low-resource countries. Non-structural protein 3 (NS3) is a multifunctional protein critical in the virus life cycle and has been identified as a promising ...
Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function
(Company of Biologists, 2014-01)
Protein degradation by the ubiquitin-proteasome system in neurons depends on the correct delivery of the proteasome complex. In neurodegenerative diseases, aggregation and accumulation of proteins in axons link transport ...
Mechanical Properties of Chaperone BiP, the Master Regulator of the Endoplasmic Reticulum
(IntechOpen, 2018)
Immunoglobulin heavy-chain-binding protein (BiP protein) is a 75-kDa Hsp70
monomeric ATPase motor that plays broad and crucial roles maintaining proteostasis inside the cell. Its malfunction has been related with the ...
Different protocols of physical exercise produce different effects on synaptic and structural proteins in motor areas of the rat brain
(ELSEVIER SCIENCE BVAMSTERDAM, 2013-05-02)
The plastic brain responses generated by the training with acrobatic exercise (AE) and with treadmill exercise (TE) may be different. We evaluated the protein expression of synapsin I (SYS), synaptophysin (SYP), ...
Thermodynamic origin of cooperativity in actomyosin interactions: The coupling of short-range interactions with actin bending stiffness in an Ising-like model
(AMER PHYSICAL SOC, 2009)
We present Monte Carlo simulations for a molecular motor system found in virtually all eukaryotic cells, the acto-myosin motor system, composed of a group of organic macromolecules. Cell motors were mapped to an Ising-like ...
Cyclophilin-A is bound to through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex
(American Society for Biochemistry and Molecular Biology, 2004-10-20)
Although cyclophilin A (CyP-A) is a relatively abundant small immunophilin present in the cytoplasm of all mammalian cells, its general function(s) in the absence of the immunosuppressant drug cyclosporin A is not known. ...