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Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death
(Pergamon-Elsevier Science Ltd, 2017)
Mesenchymal stem cells (MSCs) are multipotent cells characterized by self-renewal and cellular differentiation capabilities. Oxysterols comprise a very heterogeneous group derived from cholesterol through enzymatic and ...
Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission.
(American Society for Biochemistry and Molecular Biology, 2005-11-19)
Galectins have emerged as a novel family of immunoregulatory proteins implicated in T cell homeostasis. Recent studies showed that galectin-1 (Gal-1) plays a key role in tumor-immune escape by killing antitumor effector T ...
Permeability transition pore regulates both mitochondrial membrane potential and agonist-evoked Ca2+ signals in oligodendrocyte progenitors
(Churchill Livingstone, 1999-09-01)
In this study, we investigated the importance of mitochondrial permeability transition pore (PTP) in agonist-evoked cytosolic Ca2+ ([Ca2+](c)) signals in oligodendrocyte progenitor cells (OP cells). We measured transmembrane ...
Saturated Fatty Acid-Induced Insulin Resistance Is Associated With Mitochondrial Dysfunction in Skeletal Muscle Cells
(WILEY-LISS, 2010)
Increased plasma levels of free fatty acids (FFA) occur in states of insulin resistance such as obesity and type 2 diabetes mellitus. These high levels of plasma FFA are proposed to play an important role for the development ...
Influence of glucose metabolism on vascular smooth muscle cell proliferation
(Hans Huber, 2013)
Diff erentiation of vascular smooth muscle cells (VSMC) is
an essential process of vascular development. VSMC have
biosynthetic, proliferative, and contractile roles in the vessel
wall. Alterations in the diff erentiated ...
Efeitos do herbicida a base de glifosato sobre o encéfalo de peixe-zebra (Danio rerio)
(2018)
Glifosato (N-fosfonometil-glicina) (GLI) é o ingrediente ativo dos herbicidas mais utilizados em todo o mundo. O GLI é aplicado em produtos formulados, denominados herbicidas a base de glifosato (HBG) e tais formulações ...
Análise do estresse oxidativo e morte celular por material particulado da queima da Amazônia e compostos isolados
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM BIOQUÍMICA, 2016-09-19)
In recent discussions on environmental issues, air pollution has been considered an important environmental risk factor, and, consequently, a burden to human health. Several poluents are released daily by natural or human ...